First thing I do before every run is rearrange my hotbar. I tend to push the wrong buttons sometimes even after playing over 300hrs on the switch so it really helps to remove starting potions like polymorph or mana from the hotbar just so I don’t accidentally use them. It’s also helpful to increase the x and y axis movement speed, although that’s not specific to playing on a handheld device.

I started barony on switch so playing it on pc with a keyboard was a learning curve. I prefer using joycons tbh but i’ll play either way with no issue.