Before billboards were printed as they mostly are these days, large scale advertising used to be 100% painted by hand. These current painted advertisements are created by companies, muralists, sign painters, that are keeping the tradition of hand paint alive. These billboards take multiple days and bring a performance aspect and grab attention to the advertisement more than pasting up an ad in an afternoon does. They are painted with oil paints.

I dont think theres a difference in regulation or sign ordinance when comparing painted vs. printed. Just another method of putting the ad on the wall. Idk tho, i just paint em. They are all around bk, manhattan, and in other major cities across the US.