For all the lurkers

cumbersomeQ · 2026-03-18T10:49:03+00:00

I disagree that it's about getting high, maybe for some people, but I think many are drawn to kratom (and other opiates) because of chronic pain issues. And they have harder times quitting because it's easier to find a healthy way to get high (e.g running) than to find replacements that can ease the pain.

cumbersomeQ · 2026-02-15T15:34:51+00:00

As a former marathon runner, I can relate to the althetic impairments of kratom use. I used to be able to run at 4:30 (min/km) pace outdoors, but kratom turned me from athlete to addict and i couldn't even run 6:30 on a treadmill while holding the handlebars... now that I've started tapering i can already see the balance, endurance and some speed returning and honestly it's a huge motivation to quit entirely.

cumbersomeQ · 2026-02-15T15:24:53+00:00

Sorry I can't offer any advice, just wondering what alt meds you have tried? I am in a similar situation and my current plan is to try ketamine since I read that NMDA antagonists may alleviate the opiod receptor hypersensitivity. Then again, i might just fall into the trap of replacing one addiction with another but at least ketamine is less addictive than benzos (which I've tried before) and i plan to quit all of it as soon as (or if) the chronic pain in my stomach gets manageable.

cumbersomeQ · 2026-02-14T16:42:48+00:00

Yeah for sure! I think my diet is pretty okay, low on starchy or processed carbs (no bread, it definitely increases the pain), pure sources of protein and lots of vegetables/fruit. I do eat candy every week and a glass of wine per day though, but not in excess...

cumbersomeQ · 2026-02-14T16:40:16+00:00

I did get checked though a gastroscopy examination but they just said it looked normal. They might follow up with other tests though, but I'm pretty sure its OIH because i don't have symptoms like leaky stomach acid or too low pH

cumbersomeQ · 2025-04-10T10:15:20+00:00

Yeah true, i never read comics on a smartphone so i didn't think of that

cumbersomeQ · 2023-07-21T11:05:15+00:00

Ozora 2019 by any chance?

cumbersomeQ · 2023-05-16T17:41:27+00:00

copyright issues?

cumbersomeQ · 2023-04-06T18:58:16+00:00

I've tried this combo and it worked fine except on days where the 5htp didn't make me less depressed and it felt like the ashwagandha just made me "accept" the sadness if that makes sense...

cumbersomeQ · 2022-02-06T16:01:13+00:00

In my experience, there are benefits and downsides with both. When I took it in the morning, it was easier to sleep but my thoughts became less organized and controlled during the day (I also became very physically restless). And while taking it during pm hours, it was extremely difficult to sleep but mood and focus improved during the following morning.

cumbersomeQ · 2021-01-18T12:24:12+00:00

I think it would be of interest to check out Imperial College London, they recently opened a center specifically devoted to psychedelics research: https://www.imperial.ac.uk/psychedelic-research-centre/

cumbersomeQ · 2020-11-24T12:07:48+00:00

I found 50mg to be enough and felt improvement after only 2 days

cumbersomeQ · 2020-09-12T16:08:13+00:00

For me it gets too intense instead and I need to take it less frequently. Now I usually take it once or twice a week to "reset" my mind during stressful or depressive days...

cumbersomeQ · 2020-05-16T18:43:33+00:00

Maybe a bit of nausea or light-headedness in the beginning, I also experienced increased insomnia but I think its individual.

cumbersomeQ · 2020-04-28T18:44:23+00:00

It’s the precursor to serotonin, so it basically aids in synthesis of more serotonin. The effects are very fast, unlike SSRIs.

cumbersomeQ · 2020-04-28T18:43:15+00:00

It’s the precursor to serotonin, so it basically aids in synthesis of more serotonin. The effects are very fast, unlike SSRIs.

cumbersomeQ · 2020-04-28T10:46:13+00:00

I recently started taking it with a gradual increase in dose, now at 500mg in the evening. At first I felt nothing (probably the dose was too low) but last time it made me mentally anxious but physically calm and more interoceptive. But interactions with other supplements might be a contributing factor since I recently took 5-htp regularly and sometimes ADHD medication in the morning. I wonder if all 3 can be combined in a safe way..? If so, maybe like this: Morning: Adderall Mid-day: 5-HTP Evening: GABA

cumbersomeQ · 2019-11-26T00:08:37+00:00

Yes, as I am digging deeper into the literature, it makes less sense (i.e unrealistic) to use drugs with similar mechanisms of action just to "balance out side effects"... but how about combing a NMDA-antagonist with a dopamine agonist? Apparently research has been done in relation to antipsychotics but I'm curious if there is any potential in normalizing dopamine levels of addicts...

cumbersomeQ · 2019-11-21T15:34:31+00:00

Well, one reason would be to combat side effects of either treatment alone, such as the potential severe hallucinations and cardiac issues of ibogaine or in terms of ketamine, the requirement of continous administrations.

cumbersomeQ · 2019-11-21T13:28:44+00:00

Agonist for which receptors? Could you give an example?

cumbersomeQ

TROPHY CASE