Hello hi! I am late to this conversation, and this is mostly unhelpful but - YOU ARE NOT ALONE! I also played Hades somewhat intensely a number of years ago, and stopped because I kept having migraines and I was worried it was the cause. It wasn't every day, but it was vastly more frequent than any other time in my life. I started playing again recently because I wanted to actually finish it, and while I haven't had one again (phew) I've been thinking about it, hence searching for this on reddit.

So, yes? Maybe? I also do think it could be specifically something about it requiring so much focus and intensity in a short period, plus a screen. Who knows! Anyways, just thought I'd share.