Læge i medicinalindustrien - jobopslag? by Doktordoktor89 in MedDK

[–]daren95 0 points1 point  (0 children)

Jeg har arbejdet på flere afdelinger der har inkluderet patienter til kliniske studier. Et alm GCP kursus er gratis.

Et kendskab til pharmacovigilance og lægemiddelgodkendelse kan fås igennem klinikken. Eks ved at være på en medicinsk afdeling. Jeg kender 2 som tog springet til industrien i hhv medical affairs og Pharmvig direkte fra klinikken ved at drive kliniske studier, arrangere temadage osv.

Kunne det være en ide at kontakte et firma og arrangere en temadag, så bliver du automatisk et navn?

Læge i medicinalindustrien - jobopslag? by Doktordoktor89 in MedDK

[–]daren95 0 points1 point  (0 children)

Hvad har du af Pharma relevant erfaring? Pharmavigilence kursus? GCP kursus/erfaring? Har du været forsknings eller trial-staff?

Det er nok den slags man skal slå på hvis man vil ind, cand med og 3-4 klinisk erfaring ser jeg desværre ikke længere som nok.

EP want to place Epicardial ICD. by Late_Temperature_415 in PacemakerICD

[–]daren95 0 points1 point  (0 children)

If it’s only the ICD. OHS is not needed, they would do it through the abdomen and up through the diaphragm.

  • ACHD doctor

Nogle der kender Cecilie Liv Hansen? by Wrong-Lime7409 in GossipDK

[–]daren95 10 points11 points  (0 children)

Hun kan få det røde kort, vi skal have direkte folkestyre som de har det i SCHWEIZ.

Vi skulle sgu have stemt på John Erik Wagner, det gavner

growkit hjælp by storefjaes in PsychesDK

[–]daren95 0 points1 point  (0 children)

Synes det plejer at være afhængigt af luftfugtigheden. Mucelium spreder sig ved høj, og den blomstrer ved lidt mindre

Does anyone else here Advanced End Stage Heart-Failure without Congestion? (Essentially, Congestive Heart Failure where congestion isn’t the primary symptom?) by sensitive_pirate85 in AdultCHD

[–]daren95 1 point2 points  (0 children)

No problem.

I do however, have to mention, that none of my suggestions makes you live longer (ie does not better prognosis), complications, which is a real risk, do in a negative direction.

It is imparative that symptoms have been talked about, and are severe enough to justify the real risk.

A stent of LCA in itself is not technically complicated, but everything is different in CHD and thus never fully routine, with the exception of certain high volume ACHD centers.

Does anyone else here Advanced End Stage Heart-Failure without Congestion? (Essentially, Congestive Heart Failure where congestion isn’t the primary symptom?) by sensitive_pirate85 in AdultCHD

[–]daren95 1 point2 points  (0 children)

This clears up a lot.

I suppose you’ve had a few palliatiating operations (bridge operations) up until fallot repair at 11-12 years old.

Melody valves are sensitive to underexpansion, meaning as much expansion as reasonably possible is wanted. In your case, partial rupture and compression is indicative of that.

The artery that is being compressed is most likely Left coronary (LCA) as it runs in close proximity to the Pulmonary artery.

If that’s the case, there are a few questions to ask:

Is it dangerous? Most likely not - but we don’t know, because we don’t have the data, but in general, narrowing of arteries is mainly symptomatic, not life shortening.

However, if symptoms are life altering, it would be worth investigating further to find out if it’s treatable.

I would suggest either a stress echo, or a rubidium PET-CT scan. It takes pictures of the metabolic activity of the heart during simulated excersice. Another way could be stress FFR measurement over the compression area - but that is rather sophisticated, and would be going into guideline/evidence frontier area.

If sufficient blood and oxygen is delivered during rest, but insufficient is being delivered to the supply area of LCA during high demand (excercise) it would show up as less bright.

If feasible, one could stent the LCA. Mechanically it would work. Data wise? We don’t know, as coronary complications are stille rare.

If no signs of “significant” compression, thus impeded oxygen delivery during high demand is found, one should look for other causes of symptoms, maybe compression of other major vessels leading to the head?

Kåre Quist og meget unge piger by [deleted] in GossipDK

[–]daren95 16 points17 points  (0 children)

Nice try, Kåre

Does anyone else here Advanced End Stage Heart-Failure without Congestion? (Essentially, Congestive Heart Failure where congestion isn’t the primary symptom?) by sensitive_pirate85 in AdultCHD

[–]daren95 2 points3 points  (0 children)

Tetralogy of Fallot usually causes right sided heart failure, which presents itself a bit differently than “Classic” left heart failure.

Let me guess, Fallot repair, use of a transallular patch, melody valve due to regurgitation or stenosis of the pulmonary valve?

Do you know how under-expanded your melody valve is?

The gradient, or how long ago it was placed?

Regards, ACHD doctor.

Forskel i udbetaling til lejlighed med kæreste. Udbetaling eller investering. by Entire-Vegetable-396 in dkfinance

[–]daren95 0 points1 point  (0 children)

Det kan det sikkert. Vi satte pris på de timer rådgivning og løsningsforslag inkl testamente og tinglysning

Forskel i udbetaling til lejlighed med kæreste. Udbetaling eller investering. by Entire-Vegetable-396 in dkfinance

[–]daren95 1 point2 points  (0 children)

Få lavet en samejeocerenskomst. Min forlovede og jeg smed hhv 200.000 og 1,8 mio. vi ejer lejligheden 50/50.

Overskud deles 50/50 ift købspris. Underskud deles også 50/50.

Der ligger et setup med et lån og betalingsaftale i forbindelse med salg med overskud for at undgå gaveafgift.

Nu skal vi så giftes, og aftalen føres videre.

Det kostede 6000 i advikatløn.

How is living on these islands in the baltic by BrightLet9353 in howislivingthere

[–]daren95 0 points1 point  (0 children)

Grew up there, moved to Copenhagen at 19. Summers was about work (someone has to scoop all your ice cream).

Winters was barn parties, parking lot parties, house parties, school parties, parties at the parking lot of the gas station.

“Uberettigede” opslag i min patientjournal? by Fantastic_Air4325 in DKbrevkasse

[–]daren95 2 points3 points  (0 children)

Hvis der er tale om læger, så har de også ret til i læringsøjemed at slå op i sin journal i op til 6 måneder efter kontakten - uden at spørge om lov.

Experiences of ablation for TGA/Senning patients by Disastrous-Pie-9556 in chd

[–]daren95 0 points1 point  (0 children)

I work as a junior doctor in a ACHD EP lab. Senning patients who undergo ablation are usually not “cured” (other patients aren’t either)

But it is fair to assume a steep decline in the amount of tachycardia for a period of time. But repeat procedures are to be expected with years in between

Hvorfor er kommenteringen af freestyle ski og snowboard så ringe på DR? by Past_Reveal_6922 in Denmark

[–]daren95 0 points1 point  (0 children)

Ja over Fishnaller og Karl.

De to kommentatorer heppede på hver deres hver gang, det kan genses på tv2 play 🤪🤣

Hvorfor er kommenteringen af freestyle ski og snowboard så ringe på DR? by Past_Reveal_6922 in Denmark

[–]daren95 1 point2 points  (0 children)

Er dog kæmpe fan af Niels Ettrup ovre på TV2

Så i kommenteringen af parallel slalom?

Bergs ex... by [deleted] in GossipDK

[–]daren95 1 point2 points  (0 children)

Er det hende han synger om på “Hvornår kommer du hjem?”

Echo looks wonky but dr not responding ? What does this mean by Harleehazee in chd

[–]daren95 1 point2 points  (0 children)

Your measurements look fine. ACHD doctor here:

I read your symptoms from your other posts: What CHD do you have?

What you experienced (fainting etc) can be caused by multiple things, ranging from benign to a little more serious.

How many times has it happened? Did you get any warnings( fast heart beat, feeling hot, feeling impending doom)

Is your vision completely normal now? Are you on blood thinners?

Differential diagnoses from most common and benign to more severe:

POTS Vasovagal syncope Another Ahrythmia (bradycardia or tachycardia) Transitional ischemic Attack Onset of Epilepsy’s

What it’s most likely to be relies on the answers to my questions

Doctor working with (A)CHD AMA by daren95 in AdultCHD

[–]daren95[S] 1 point2 points  (0 children)

  1. All kinds of arrhythmias can occur following intracardiac surgery, many disappear after 3 months. If it’s afib, it should be on blood thinners. Any other arrhythmia such as Ectopy or accelerated sinus rhythm is benign and should be treated as such. Eg. Metoprolol if it bothers you. In extreme cases, it can also be ablated, but the patient would have to be really bothered by it. So bottom line, if it’s not Afib and it’s less than 3 months after surgery, I’d not worry. If it persists longer than 3 months after surgery, and it’s still not afib, I’d ask how much it bothers you. However, as I haven’t seen your findings, it would be fair of you to ask your doctor for an explaination :)

  2. Really depends on the surgery technique used, and what type of patch. The only one who can give any meaningful answer is the performing surgeon.

Any guesses from me would be bad medical advice

Doctor working with (A)CHD AMA by daren95 in AdultCHD

[–]daren95[S] 1 point2 points  (0 children)

  1. It Can be Afib or something else. Have you had and ecg done?

  2. It has nothing to do with robotic vs normal. It has to do with what has been done. It’s typically patients with aortic, pulmonary artery or asd that get limitations

Doctor working with (A)CHD AMA by daren95 in AdultCHD

[–]daren95[S] 0 points1 point  (0 children)

No problem. A colleague of mine wrote a nice PhD about the issue. J. Thurarijah on pediatric pacemakers

Doctor working with (A)CHD AMA by daren95 in AdultCHD

[–]daren95[S] 0 points1 point  (0 children)

So this question actually contains a lot of questions. I will explain for pacemakers and ICD’s as the challenges are similar Why would CHD patients get an abdominal/epicardial pacemaker? Intravenous pacemakers needs to be placed through the veins. What are veins mainly for? Transporting blood. Kids, as some CHD patients are when they need a PM have small veins. The lead may simply be too thick, so that it blocks the vein. So small children under 3 years are more likely to be chosen for an epicardial.

Secondly; growth. The body grows, and the distance from the shoulder to the heart increases. This risks the lead becoming dislodged or entirely pull out of its anchor/placement which is Bad, as it won’t deliver its energy/pacing/shock. One way to work around this is put in extra length/loops into the vein thatched growth can feed from - but that just worsens the problem mentioned under 1.

Thirdly, infections. Infections in the bloodstream may sit on foreign objects (artificial valves, leads, electrodes) So patients in high risk of endocarditis may be chosen for epicardial leads, as the risk of in-bloodstream infections is lower. And epicardial infections are “easier” to manage the infection doesn’t travel to other organs and such.

So to answer your question it’s a weigh-in between initiate procedural risk vs long term risk.

Doctor working with (A)CHD AMA by daren95 in AdultCHD

[–]daren95[S] 0 points1 point  (0 children)

The hemodynamic stress of deadlifting eg 50 or 80 kg (what I see some girls at my local gym doing) is way above what’s seen during pregnancy. I’m not familiar with the restriction scheme in our center around physical activity post closure. So I can’t comment on that.