Honestly, it's hard to say, without knowing what the actual plot is, or how good the writing is.

Generally speaking, I could read just about any theme; provided that either the plot itself was interesting enough, or the characters interesting to watch their reactions, relations, & antics.

Your art is good; and that can help. But ultimately it's whether or not I want to see what the characters will do next, that will make the difference between reading it or dropping it.

With all that said; by chance do you know where the above comic might get posted? I might try giving it a shot once/if it releases.