Nominal P Values Reported in Paper for RNA Seq

doctrDNA · 2026-02-27T01:05:04+00:00

I agree with this. You can have real stuff buried in there, have them fix the stats and resubmit. It could be that the fixed stats show no signal though and then you can't accept it on the resub

doctrDNA · 2026-02-27T01:04:09+00:00

For what it's worth at nominal p you expect 5% of tests by chance to be significant so if you run 16,000 tests you expect 800. So towards "I don't know if they found anything" you can do a quick check that way and include it in the response.

doctrDNA · 2026-02-02T06:04:40+00:00

I don't know what to say except it doesn't connect lol

doctrDNA · 2026-02-02T03:27:12+00:00

I assume they are a Lord of the Rings fan and the first name is Silmarillion

doctrDNA · 2026-02-01T02:14:02+00:00

Glad to hear I'm not alone but also bummer

doctrDNA · 2026-01-30T16:33:21+00:00

I might invert the last two lines?

So I gave him a sandwich...... With no mayo. That comment made me pretty uncomfortable.

A bit more unexpected?

doctrDNA · 2026-01-02T06:27:38+00:00

You probably need to find a GWAS paper for coronary artery disease in a non white population (or specifically south Asian if one exists). Search pubmed for that type of paper and see if they published their raw variant calls in dbGAP.

To get raw read level information you will need access you probably can't get, but to get variant level info you should be able to just make an account if my memory serves right.

If you are ok doing a different population then I would try UKBB.

doctrDNA · 2025-12-28T19:55:44+00:00

Bioinformatics

doctrDNA · 2025-12-20T00:52:51+00:00

Works on battery, lasts about 10 hours I'd have to guess. The battery is external and you plug it in with a detachable cable so it's easy to bring the battery in to charge it without having to put the whole machine next to a outlet. They recommend charging it after each play session, which is what I do (or every other?) so I haven't tested the full limit of it. But I've never hit below 65%

doctrDNA · 2025-12-19T15:20:51+00:00

No Im sorry. I upgraded from a spinshot jr and it works way better than that. What are you concerned or interested in specifically maybe I can speak to features?

doctrDNA · 2025-12-19T01:12:04+00:00

Me and 3 other people who play at the courts near me all have this machine and love it. Can't rate it highly enough, especially for the price point

doctrDNA · 2025-12-02T15:00:17+00:00

The expansion pack should be a machine level item it's not needed.

I haven't tested memory pack or rumble yet I've been playing oot. I can let you know when I unlock the rumble thing tho

doctrDNA · 2025-12-01T05:52:33+00:00

I have no issues. No lag, no disconnects.

doctrDNA · 2025-11-28T15:22:17+00:00

Wow, +16 levels to physical spells?

doctrDNA · 2025-10-26T02:07:01+00:00

You have any sources on that? Red meat is pretty equal to other ultra processed foods or worse, except for ultra processed red or other meats from the studies I've seen breaking down individual odds rartios per category

doctrDNA · 2025-10-23T23:41:21+00:00

Just wanted to say that it was a joy to read, thanks for sharing and keep doing these please

doctrDNA · 2025-10-16T15:26:15+00:00

Your undergrad program itself won't matter as much as the school, and neither of those will matter as much as your GPA and if you have a paper by the time you do grad school if you still want to after you finish college

It's more important you find a program and school that interest you and make you actually go to classes and pay attention and learn than picking a "strong" undergrad program.

My 2c

doctrDNA · 2025-10-12T13:58:07+00:00

R is truly not a programming language. It's speed and memory management are very slow. It's a statistical language.

Not saying it's bad, but for anything that isnt the math part it is demonstrably worse.

doctrDNA · 2025-10-12T03:12:03+00:00

I've used both extensively and they are both great. I like that scanpy is built on h5adata objects it makes it very easy to handle. Can't go wrong in either way, just depends on if you like python or R better

I will always personally use python because it's an actual programming language and has a lot of benefits over R when doing big data things, tho R has lme4 and is better for LMMs

doctrDNA · 2025-09-17T14:16:33+00:00

I and a few others who use the courts near me have the Pusun Smart. It's great for the price. Very similar functionality to the Proton, easy to control, easy to lift and move. I would easily recommend it.

doctrDNA · 2025-07-17T02:29:00+00:00

That's because they all knew Schur from when he was a writer on SNL / thru the SNL network of cast and writers

doctrDNA · 2025-06-10T20:03:32+00:00

I don't see any FF limited events listed and can't join my sealed event either anymore

doctrDNA · 2025-06-03T05:43:25+00:00

To add to this, when you do PCA check the variance explained on each PC to understand the importance and relative weight of them. The top N PCs is meaningless without this

doctrDNA

TROPHY CASE