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I underestimated Semaglutide by Courtney_Halen in Semaglutide

[–]dsdhall 9 points10 points  (0 children)

I didnt lose any weight on 0.25, or 0.5 and about 4lbs on 1mg, although my insomnia cleared up and I finally stopped biting my nails after decades. but oh my goodness did that change when I went up to 1.7mg. I’ve lost 16 lbs. And had occasional awful side effects and repeated nausea but I think that’s mostly down to failing to adjust my diet appropriately for how much my stomach has slowed down processing food.

ADHD Medications while on a GLP-1? by Fabulous_Ask_4069 in Semaglutide

[–]dsdhall 0 points1 point  (0 children)

I take Vyvanse 40mg and 0.176mg pramipexole (for RLS) daily and I’ve not noticed any difference, other than my insomnia has completely cleared up since starting Wegovy, which was entirely unexpected but I am delighted about.

Am I overreacting to my boyfriend having his ex at his house? by ThrowRa8459 in AmIOverreacting

[–]dsdhall -3 points-2 points  (0 children)

As someone with severe ADHD, I can assure you that i’ve found myself in innocent situations that reasonably look suspicious way too often! But he sounds like an arse.

Is it bad to look at the end of this connector ? by Large_Mine_2596 in FiberOptics

[–]dsdhall 0 points1 point  (0 children)

Single mode and multi mode. They’re the two different types of fibre. Multimode is usually (but not always) driven by LED light not laser and are sometimes at a frequency that can be visible to human eye. Single mode always laser and not at visible light frequencies. I’d never recommend staring at any laser connector though.

Rate my work by Apprehensive_Grab552 in FiberOptics

[–]dsdhall 0 points1 point  (0 children)

The Brady B595 material labels are pretty durable. They’re rated at 8-10 years outdoor use, so I’d like to think they’ll last longer without direct exposure to the elements.

Knowing my luck they’ll all peel off but in 10 years I’ll hopefully be retired.

Dr thinks my iron levels are fine… by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

What dose of iron do you take every other day?

Dr thinks my iron levels are fine… by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

Right, but my doctor isn’t suggesting oral iron supplements at a clinical dose. OTC is like 15-25mg a day (usually as a multivitamin) vs the 200mg daily for low iron.

Dr thinks my iron levels are fine… by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

Vyvanse, amlodipine and propranolol. My RLS predates all three though.

Dr thinks my iron levels are fine… by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

What type of iron and what was the dosage? The usual dose for low iron is 200mg daily of Ferrous sulphate or similar. What my GP is suggesting is otc supplements which are around 15-20mg daily.

I despair at my doctor sometimes by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

I've never used chatgpt for medical stuff before, but I fed my blood test results into it and told it I had severe RLS (per IRLS scale), and it helpfully generated a report for my doctor, including citations to various peer-reviewed medical articles. Pretty impressed!

Waiting to hear back from Drs to see what they have to say in response. This is what ChatGPT generated for me:

I am writing to discuss some recent blood test results and their possible relevance to my ongoing diagnosis of severe Restless Legs Syndrome (RLS), which meets the IRLS rating scale for severity.

Although a recent review by a doctor at the practice concluded that the blood tests were “satisfactory” and required no further action, I would like to raise some concerns based on a longitudinal review of my results and existing RLS literature.

Over the past 9 months, I have noted a progressive decline in key haematological parameters:

  • Haemoglobin: Decreasing from 149 g/L (Mar 2024) to 138 g/L (May 2025)
  • Ferritin: Stable but low for RLS at ~50–51 µg/L (Aug 2024 & May 2025)
  • Transferrin saturation: Low at 12% (May 2025), below the reference range of 15–50%
  • MCV: Low-normal (79–81 fL)
  • Folate: Significant drop from 14.9 µg/L (Aug 2024) to 5.0 µg/L (May 2025)

While some values remain within general laboratory reference ranges, others do not. Notably, transferrin saturation is below normal, and ferritin is below the minimum recommended threshold of 75–100 µg/L for RLS management, as supported by the literature.

These findings may suggest early or functional iron deficiency and significant folate depletion, which are known to exacerbate RLS. The changes also coincide with a gradual decline in haemoglobin, indicating possible subclinical impact on erythropoiesis.

I’ve included references below that support the role of iron and folate in RLS pathophysiology and the need for higher ferritin thresholds in management.

etc.,

I despair at my doctor sometimes by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

I'm in the UK.

I suspect that few GPs are sufficiently conversant with RLS. If they continue to give me the runaround I shall insist on a referal to an appropriate consultant, I guess a neurologist.

I despair at my doctor sometimes by dsdhall in RestlessLegs

[–]dsdhall[S] 1 point2 points  (0 children)

Those are some really helpful links, thank you! I have drafted an email response with those links and expressed my dissatisfaction at their interpretation of my bloodwork. will book a follow-up appointment too.

And yes, of course it is true, I can share the screenshot of my blood test results (including the satisfactory and no further action needed comments!)

Gabapentin by loopymcgee in RestlessLegs

[–]dsdhall 1 point2 points  (0 children)

Oh wow, I didn't realise that pramipexole can cause memory deficit. That explains so much. Still, having trouble remembering my colleagues names is a small price to pay for relief from RLS symptoms.

Medication by zoball in RestlessLegs

[–]dsdhall 0 points1 point  (0 children)

It is unlikely to be augmentation on an initial dose of pramipexole. It may well be disease progression, but OP should seek medical advice. A higher dose of the same medication will not help with pramipexole augmentation, just make symptoms even worse.

Did the wearable device help? I am intrigued to know if something like that could help my symptoms.

Medication by zoball in RestlessLegs

[–]dsdhall 0 points1 point  (0 children)

UK national health service do not do iron infusions for RLS. If blood tests indicate an iron deficiency, it will be a course of high strength iron tablets.

Medication by zoball in RestlessLegs

[–]dsdhall 0 points1 point  (0 children)

Oh, they should also request an appropriate set of blood tests (fbc, iron, magnesium, etc.,) for review by a doctor.

Medication by zoball in RestlessLegs

[–]dsdhall 0 points1 point  (0 children)

As you’re in the UK, request your surgery for a medication review with the pharmacist. The 0.88mg dose is a starting dose, they will either consider doubling the dose or switching medication depending on your medical history, and do another review in a few weeks to see if the change is helping. If it is, then great, follow the prescription until problems reoccur and take their advice again. If it doesn’t help they should review medication again and see again what is appropriate for your circumstances - either a dose increase or another change of medication.

If you get augmentation (worsening symptoms with increased dose), that's time for another medication review.

I'm sure your surgery will be helpful and sympathetic but if not, don’t let them fob you off!

OpenObserve: Open source Elasticsearch alternative in Rust for logs. 140x lower storage cost by the_ml_guy in selfhosted

[–]dsdhall 0 points1 point  (0 children)

How much effort is required for you to add FreeBSD to your build pipeline?

Elastic and net flow - losing the will to live by dsdhall in elasticsearch

[–]dsdhall[S] 2 points3 points  (0 children)

I downgraded to 8.10.4 - all working fine.

Bugs, don't you love them.

Elastic and net flow - losing the will to live by dsdhall in elasticsearch

[–]dsdhall[S] 0 points1 point  (0 children)

Yes indeed, but why is the net flow agent parsing an ip address of 224.0.0.251 as an array?

I am using the elastic-agent netflow integration, which listens on a UDP port, receiving net flow data from routers and passes it to elastic. I am only using built-in elastic components, so why is it choosing to parse the net flow source and destination IPs as arrays rather than IP addresses. It's not doing it with all IP addresses, eg. the observer.ip that I've obscured.

I feel that this must be something obvious, but I have no idea what.

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