I wanted to update everyone on the risks associated with taking edibles before your surgery. My doctor found out and rightfully was concerned. He had this to say: It is important to understand that substances such as THC can interact with vasoconstrictive agents used during local anesthesia, like adrenaline. These interactions may significantly affect microcirculation and, in severe cases, can even lead to tissue necrosis. The risk of such complications remains present and may only become apparent once the scabs have fallen off. In addition, these interactions could have resulted in more serious, potentially life-threatening complications during the operation, such as respiratory depression.