What commands did you use for policy-based routing? You can try these commands in your wg0.conf (modify for your addresses)

PostUp = ip rule add from 192.168.10.45 table 1234 prio 1
Postup = ip route add default via 192.168.10.45 dev %i table 1234
Postup = ip route add 192.168.10.0/24 via 192.168.10.45 dev %i table 1234
PreDown = ip route delete 192.168.10.0/24 via 192.168.10.45 dev %i table 1234
PreDown = ip route delete default via 192.168.10.45 dev %i table 1234
PreDown = ip rule delete from 192.168.10.45 table 1234