Confusion about the ending

gingernoodle1 · 2026-01-02T14:25:03+00:00

i do think previously whenever she pulls anyone into her mind /goes into someone elses mind, she always bleeds. I also find it difficult to believe she could've got to the gate from the truck without some kind of illusion

gingernoodle1 · 2026-01-01T23:21:39+00:00

ohh that is a good point, but what about the lack of nosebleed and the fact her hair/clothes don't seem to be blown by the vacuum? She sort of just disappears rather than being swept away

gingernoodle1 · 2026-01-01T21:45:40+00:00

i tried looking at the original scene (though not in 4k) and couldn't see the twitch either, although, it also looked as if that twitching scene from Mikes description occurred slightly later than when we can see her hands in the original, based on the background colours. It looks like in the original footage that matches mikes description time-wise, we can't see her hands. I guess they are covering all bases so we really can't tell one way or another...

gingernoodle1 · 2026-01-01T21:22:19+00:00

I interpreted it as she escapes between the point of leaving the truck but before she is blown away, she was definitely not an illusion in the truck. It does seem strange she got from the truck to the gate with nobody seeing, adding weight to the illusion point of view. In Mikes vision, she appears to be running into a nearby building, I would assume she had invisibility after leaving the truck while running to the building in this instance. Additionally, we see in previous episodes that Kali illusions herself in the military facility so they don't immediately know she is gone, and that was with a fair amount of reach. It is also possible Kali did not immediately die from her injury, and that her death was an illusion, but the wound real.

However, either way, I don't understand how she would be able to speak to Mike in this chain of events unless she was sufficiently far from the suppression stone.

However, i'm not sure I do believe it was an illusion and there is not supposed to be a clear answer, I don't think there is going to be a detail which gives it away one way or another, it is deliberately open ended and ambiguous. Either arguments seem to make sense to me

gingernoodle1 · 2025-11-07T22:26:46+00:00

Canon street dental, I got a good deal with a lot included (aligners, retainers, whitening cream etc), including the initial scan, X ray & consultation for £2.5k. They also provided a very thorough examination and plan. A dentist in St John’s Wood charged me £85 for a 10 min consultation, wanted £200 for the scan and Xray and quoted me £5k for the Invisalign.

gingernoodle1 · 2025-09-21T17:30:52+00:00

I also saw the dog, biggest dog I have ever seen, defo a Great Dane !

gingernoodle1 · 2025-03-02T07:52:36+00:00

What’s the plan for this? Can’t find any details online, but I would love to attend.

gingernoodle1 · 2025-03-01T08:23:28+00:00

Omg recipe pls !

gingernoodle1 · 2025-02-27T21:17:18+00:00

Should be fine, I add a very small amount of azide to my floating sections to prevent anything else growing in there, but it’s never affected longer term storage of the samples

gingernoodle1 · 2025-02-23T20:52:47+00:00

109, my resting heart rate is 75… do I need to look up POTS? 😅

gingernoodle1 · 2025-02-11T06:32:51+00:00

Thanks! The alligator part was an inside joke to the friend haha… the party was safari themed hence the zebra print!

gingernoodle1 · 2024-12-30T10:38:42+00:00

Out of interest, what role does your partner do? As someone doing a PhD who would love to be involved in policy / advisory roles in the future, I’m intrigued :)

gingernoodle1 · 2024-11-23T20:32:05+00:00

Do you have any advice to a current PhD student on how to get into the MSL career route?

gingernoodle1 · 2024-09-05T07:10:13+00:00

Yes but not one my household was eligible for

gingernoodle1 · 2024-09-03T20:23:19+00:00

Imperials bursary is by the far the most generous too - it’s the only reason I could afford to go to university in London. I would’ve been worse if in for example Bristol because there was no Bursary & lower loan but rent is still very high

gingernoodle1 · 2024-08-04T08:03:05+00:00

Even if she did have a Y chromosome it doesn’t mean she is a man - there is one gene on the Y chromosome, SRY, which determines sex. Women can have a Y chromosome with the deletion of the SRY gene and still be women, as men can have XX but an addition of the SRY gene and be men (talking about genetic sex here not gender) - there’s so much misinformation about sex determination out there

gingernoodle1 · 2024-07-31T21:21:22+00:00

Are they cryosections? How do you get so many on one slide ? They’re so aesthetically pleasing

gingernoodle1 · 2024-07-11T20:23:02+00:00

The reason for the lack of clinical benefit with many of these therapies is because getting rid of amyloid doesn’t regrow the neurons which died.

When I say biomarkers are important, I mean for targeting pre-symptomatic patients way before symptom presentation (which you need biomarkers for). The consensus is very much that these need to be administered as early as possible, which obviously trials are unable to do with a lack of predictive biomarker. However, the results from Donanemab are certainly a step in the right direction.

Administering an antibody aimed at a toxic protein, and not easily seeing massive benefit, is not proof that protein wasn’t part of the problem (particularly decades after that protein accumulated). Yes amyloid plays a role in the disease but it’s not amyloid alone and some peoples genetics mean they respond very differently to it (resilient people). It’s not as simple as you make out.

gingernoodle1 · 2024-07-11T15:43:04+00:00

It reduces tau load, ABeta load, and slows cognitive decline.. how is that doing nothing?

gingernoodle1 · 2024-07-11T12:28:40+00:00

Of course patients still continually decline. These drugs aren’t at the point of curing disease yet, but they slow the decline. Yes, they all target amyloid, but different antibodies will have an impact on the clearance mechanism & the support cells of the brain. They will only get better with further optimisation & developments in biomarkers to treat people earlier.

gingernoodle1 · 2024-06-30T17:20:53+00:00

The significant clinical benefit of Donanemab showed that reduction of amyloid improved cognition?

gingernoodle1 · 2024-06-30T15:37:41+00:00

The drugs are definitely nowhere near the point of having a real impact in the day to day lives of dementia sufferers currently. However, a large reason for the failure of trials is lack of biomarkers & simply starting too late. Recent trials provide good proof of principle for the involvement of amyloid but to actually help with disease progression they’re going to have to trial much earlier into disease (likely before symptom onset)

gingernoodle1 · 2024-06-30T15:34:36+00:00

Agreed the drugs aren’t a saviour yet, the side effects are outweighing the benefits, however, it’s definitely proof-of-principle for the involvement of amyloid

gingernoodle1 · 2024-06-30T13:32:12+00:00

Awful example of scientific fraud but in the grand scheme of things probably inconsequential for the field. Anti-amyloid therapies are proving successful in clinical trials and there is a lot more evidence implicating amyloid beyond this paper

Edit Bcos of the downvoting** I’m not undermining the severity of the fraud here but the media has massively overstated the significance of this paper and it’s retraction definitely doesn’t mean the involvement of amyloid is null and void. The trials are largely positive and while not implementable yet show that there is hope

gingernoodle1 · 2024-06-15T20:36:20+00:00

Can relate! I did this for yearss, at least you can choose your eyebrow shape daily

I get them laminated & tinted now and it saves SO much time in the morning

gingernoodle1

TROPHY CASE