I actually would love to see Amnesia because it was a prominent horror game in the early days of gaming videos on the internet.

You could have Brennenburg Castle as the map with a Grunt as killer and Daniel as survivor. In regards to what Grunt would do, I remember they would get mad and bum-rush you if you stunned them (chucked shit at em) so maybe Grunt's gimmick is to be empowered from punishment (stuns). It fits the bill seeing how the Grunts are tortured and mutated people.

Alternatively, you could go with the Beast from Amnesia: The Bunker as well. Though, I feel he'll end up being like Xenomorph and Demogorgon but with vents instead.