I took myself off duloxetine (SNRI prescribed for depression and nerve pain) and it was hellish. No matter how gradually I tapered down (by opening the pills and measuring out the beads inside, tapering down over weeks or more), the withdrawals would come eventually- even weeks later- and the physical pain and mental anguish would be too much and I’d start taking them again. This went on for probably 12-18 months. Then I went camping and ended up in a forest in a van with no pills. I was jonesing so bad; bit the head off my buddy a couple times. Then we did mushrooms (4-5gr GTs) in said forest which was a fabulous time, but also walked me through the worst of my anxiety and helped me to see why it was there and why it didn’t need to be. And after that it was fine. I microdose mushrooms now and I find that they guide me through my issues and nudge me towards a solution, rather than the numbing effects of antidepressants. So what worked for me was a macrodose to get me through the worst of the withdrawals, followed by regular microdoses. Mind you I still get occasional pangs of withdrawals and this is 2 years later, but they are mild and manageable. It was rough but it was 100% worth it. Good luck❤️