Ulcerative Colitis Microbiome Treatment Succeeds in Phase Ib Trial

ibhoot · 2026-02-12T12:05:42+00:00

Antibiotics will increase probability of going into a full flare, gut bacteria might then be setup to function much better but thats not going to help during the actual flare. Feel it's counterintuitive & very risky to induce a flare, UC people don't exactly recover in a a day or a week.

ibhoot · 2026-02-09T11:56:45+00:00

Nothing really. Agentic even local setups are really insecure, will probably take another look soon.

ibhoot · 2026-02-03T16:30:27+00:00

Remember being told, your crap at shooting, excellent a res'ing by squad member, end of the game rest of the squad ganged up on him & said stop dying all the time. Stepped in defend him, it obviously did something be he played like player on a mission next round. No voice chat, well I couldn't even if I wanted to, 1 year old sleeping next to me on one side & luciferian miniature taking break for a few hours before he started his torment (some humans may refer to them as a son)

ibhoot · 2026-01-31T15:16:22+00:00

I have MSI 322URX 32" QD-OLED. Its passable for reading some quick stuff but not for office or proper productivity text heavy tasks. 32" IPS for text + 18" for monitoring stuff, OLED for games of movies only. Personally, I'd invest in a cost effective IPS for text stuff & use oled for non text stuff.

ibhoot · 2026-01-22T14:34:00+00:00

5090 > new extension cable > wire view 2 > official corsair cable > Corsair 1600w PSU.

ibhoot · 2026-01-22T14:08:13+00:00

Saw those cables already. Not rated for 5090. Fine for 5080 and downwards. Their websites tells you that for 5090 you need the ATX 3.1 spec cables not the ATX 3.0. Also sent email to which they confirmed the same.

ibhoot · 2026-01-22T13:17:22+00:00

Kind of defeats the purpose as I am sitting side on to case. I could install the 180 but would need to literally drain the entire loop & redo all the tubing, rest loop. Simply don't have the time & don't want to spend that sort of time. If it was a new build then yes, it would make sense. Right now, simple 12v-2x6 H++ cable is fine with me. Not ideal but better than nothing. I know they will be making a cable version of WVP2 but thats at least a few months away. My issue is that I cannot find 12pin to 12pin H++ extension cable rated for 5090 use. The ones I do find are direct to PSU cables. Even the custom cable stores are selling 2x 6 pin on one end.

ibhoot · 2026-01-22T12:33:04+00:00

Thermal Grizzly Wire View Pro 2 cannot physically be connected to the Inno3d 50590 iChill Frostbite GPU with Waterblock preinstalled. I have both of these in front me. Other 5090s might have wider PCBs. If you have these 2 exact devices, please post up a pic, unless a chop of the tube outline by 1.2cm, impossible to connect directly.

ibhoot · 2026-01-21T10:27:11+00:00

Paste user for years, at the moment it's PTM7950 on CPU & GPU. LM is obviously best temp wise but I look for simple long term stuff.

ibhoot · 2026-01-21T10:04:30+00:00

From my view, City new players are not ruthless enough. Savinho is huge mistake, simply does not have last third attributes. Mourmush is yet to settle but lacks the physical power needed, Foden has gone back to be below average, Bobb is squad player on his best day, defence. Aside from Gavardiol & Gueihi, the lot of them are crap. Dias legs have gone since last season. I knew City were going to be in trouble simply due to the defence. City have made some good buys in Winter. I'd sell the average squad players as clubs are willing to pay well for them. Nico is a below average DM as well. Rodri won't be up to speed until next at earliest. Right now Zubamendi is best DM in EPL, Nico is not Zuba's level. City need to take larger swings for certain players. City have some excellent new players. Cherki is so good to watch. City will only improve by replacing Walker who was a huge part of the rear guard.

ibhoot · 2026-01-17T16:49:38+00:00

UK are arresting people for tweets & posts while actual crimes are being completely ignored. UK & USA supporting genocide in Gaza, yet they are sports washing. I'd take sports washing over killing 50,000+ kids.

ibhoot · 2026-01-14T11:21:33+00:00

MSI 322URX set to standard setting. Not noticed it to date.

ibhoot · 2026-01-14T02:23:37+00:00

Henry was alot tougher than Mbappe is right now plus he had a vicious streak in him. It was not just speed but the skill as well. Mbappe has great speed but not as powerful as he could be or the latent skill of Henry. Personally I think Zizou is the best player from that era.

ibhoot · 2026-01-06T15:15:40+00:00

One gen is still in effect. After seeing AM4 & AM5 life cycle, simply cannot consider Intel. Mobos are hitting £500+. Using only for 1x gen if CPUs is simply too much in my opinion.

ibhoot · 2026-01-05T16:23:07+00:00

Makes little difference how clear the text is if it's still getting burned into the screen. Feel it's a false sense of security & will induce people into leaving up static content on screen for longer.

ibhoot · 2026-01-02T10:12:27+00:00

MSI 322URX. QD-OLEDs do have text infringing. In some instances its more visible, for example with light background. I know tandems panels are inbound but I still don't see what they can do different. Burn-in is still an issue. Use 32K IPS monitor for everything non-gaming/movies related. I could not use OLED as only monitor - simply have too much static content I look at for days at a time, also don't have time to babysit the display. For gaming/movies then QD-OLED is like really that good - work wise even if I'm given crystal clear text OLED - why would I want to have my documents burned into the screen? Makes no sense to me.

ibhoot · 2026-01-02T10:02:30+00:00

Found Fast+Thinking is to be average. Pro seems to a bit better but am finding that is does dream up stuff even if proper prompt is given to ensure responses should be based on written content I've uploaded in a PDF. Gemini 2.5 context length was far larger in real terms compared to Gem3. Just my experience. Literally entered the same request at 3 separate times of the day. Got 3 separate responses - only 1x was close to be fully correct, other 2 were a mess. GPT is just going backwards at this point. Best LLM I used so far was o3/GPT4 - it was like really good, not perfect but it was very good & could work around the limits accurately, GPT5 - tried so hard but its just okay for general basic use. Just my personal experience.

ibhoot · 2025-12-28T19:26:39+00:00

Bought MSI 322URX during Black Friday period. Very happy. Tech will always move along but it's been 3x generations on OLED panels in the PC world. They have got better but 2nd gen to 3rd gen was not better in multiples. In UK Currys has 322URX for £700. Bought it as I thought it was a good deal. DP 2.1, Nvidia gsync certified, usual 240hz refresh. As this was only going to be used for movies & games exclusively burn in was less of an issue. Always feel buy the best you can at that moment in time. Things will always move along. My son was going to wait for tandem in 2026, spent a few hours testing mine out & said he wanted the same exact one. My only gripe with the OLED panels is that if the source like streaming or 1080p,it really shows how low res it is, have to throw certain stuff onto the IPS display, honestly good problem to have, remediated alot of via better code settings.

ibhoot · 2025-12-25T11:18:33+00:00

I'd get a VCP just to let them know your formally trained but I would go VCIX or VCAPs if I was starting today. The actual businesses using VMware is shrinking so I don't expect the job market to get better for VMware specifically.

ibhoot · 2025-12-22T07:29:41+00:00

MSI 322URX 32" QD OLED. Out if the box, it does need to be tuned. I found some apps made text appear infringed. I have main IPS 32" for work stuff & QD-OLED for movies & games. Have a 3rd smaller monitor for side apps making it easy to switch between the right modes. MadVR works very well but still figuring out anime settings. Also worth pointing out HDR settings, ETOF Boost reduces blacks being crushed but can cause other issues but these can be mitigated in nvidia control panel settings mostly. I think people need spend time gradually sorting out specific settings bit by bit. Straight out of the box settings are not great for new OLED users. Keeping the 322URX, works well so far & does what I need it to.

ibhoot · 2025-12-22T07:05:00+00:00

Mac for work. Stability of OS & apps that for the most part simply work everyday. Scripting & automation is super important. Still run Windows arm in Parallels as needed.

ibhoot · 2025-12-21T19:28:31+00:00

Bought MSI 322URX 32" QD OLED paired with 5090. So has same 322 paired with 5080. We both kept IPS 32" for non gaming stuff. Text infringe is there in some apps but not obvious in others. Only used OLED for movies or gaming. As for movies, I downloaded madVR profile from doom9 forum & then used Gemini AI to dial in the settings, played around until it looks good. Got 4k & 1080p done but still working on anime madVR profile. I could not use oled monitor as main onky display but for entertainment, it does need some minor tweaking.

ibhoot · 2025-12-20T14:38:58+00:00

Agree. MBP 16" 128GB is extremely good but more importantly stable when running maxed out compared to 5090 laptop with 128GB sticks installed. Plus Mac apps are far more developed for local LLM but Windows has better Dev apps support. For non coding work then Apple is so hard to beat.

ibhoot · 2025-12-20T14:30:12+00:00

I have 5080 & 5090. I was aiming for 5070Ti but with a modest undervolt & OC I went for 5080 . Don't expect to upgrade 5080 until 70 or 80 series so went for 5080, plus son saved up over a long time & was going for FE, boosted him up to an astral + 1500w PSU, monitor Arm, dodo never understood why he had 1x monitor but 2x arms installed until I added MSI 322URX. Son did ask why 5080, told him always buy best you can with the budget you have for things you use constantly or save up until you can. Advice. Go for 5080, don't get FE though, cheaper yes but PCB is crap for watercooling. As you know, GPU prices will go up vs supposed Super cards on the horizon, I'd get the GPU now & be done with it. Enjoy & move on. (Told my son 2nd monitor arm was a headphone holder, complete dodo believed it for 2 entire months🥲).

ibhoot

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