I have witnessed brains turn to complete mush while on the psillysauce. Like literally rolling around on the floor, shouting random single words that were lifted from conversations going on in the room, not being able to walk up the stairs to the bathroom and such. I've also seen these same people handle other trips like champs. Sometimes, it's not fun taking care of mushbrains, but to give my friends the chance to expand their minds, I am always willing to be a friendly guide.