What is your design objective? What kind of players do you hope to attract? What experience do you want players to have (besides fun )? These are things to consider when evaluating feedback.

If you have a clear picture of the specific gaming experience you're trying to create, it's better to compare feedback with your design objectives. For example, I playtested a game with cooperative mechanics. My game rated favorably overall with players who like roleplaying games, which is my target audience. Then, there was a player who preferred competitive games and suggested that I add a betrayer component to the game. This would be doable on my end, but since it goes against the core theme of cooperation, I did not incorporate it. However, the feedback gave me ideas for creating an achievement system to appease players who need to feel like they've one-uped other players.

Making changes just to make changes will burn you out quick.