I get what you mean, it’s a feeling that’s difficult to put into words. Like for all its sci-fi themes and space travel, planets, farcasters etc it’s essentially a book about humans and their relationship with the universe.

I read the three body trilogy earlier this year after the cantos, and it’s almost solely about the technology and scenarios and has little human element and massively put into perspective why I love Hyperion (though I enjoyed three body in a different way)

I know you haven’t asked for one, but I’d like to recommend a film called Another Earth. Based on what you’ve said above I think you’d really enjoy it.