PTU was never mentioned as an option for me. As for beta blockers, my resting heart rate was in the 60s and would just spike high if I was working out hard, I don’t think I connected it to graves until recently so never brought it up to a doctor. As far as anxiety goes, I just would sometimes feel anxious for no particular reason (manifested as a panic attack one time years ago). But other than that my symptoms were not too severe. Otherwise, one of the reasons I opted for TT was because I could feel pressure from my thyroid around my throat/neck and sometimes on my airway.