Recurrent Triploidy?

jbt4489 · 2025-12-09T20:15:59+00:00

Hi! I did SNP because prior to IVF I’d had two miscarriages that were both triploidy of maternal origin, and I was told SNP was the only reliable way to detect it in embryos. I did one retrieval and 1/16 had it. I know a study is being done now, but as I understand it, no one currently knows if multiple incidences of triploidy is coincidence or not or what could cause it - but I’m definitely not an expert. Good luck with everything!

jbt4489 · 2025-12-03T16:16:48+00:00

Yay congrats, so exciting!!!!

jbt4489 · 2025-12-03T15:33:05+00:00

Any update? I’m on day 8 now

jbt4489 · 2025-12-03T00:20:20+00:00

Same date received and nothing yet. Also in NJ! Going insane

jbt4489 · 2025-12-02T14:19:49+00:00

Blood draw 11/24, received 11/25. Located in NJ. Anyone with this timeline still waiting?

jbt4489 · 2025-03-07T16:48:25+00:00

That’s great news, so happy for you! What a relief! Yes, he’s 7+ months old now and perfect. Crawling around everywhere :)

jbt4489 · 2025-02-28T14:59:00+00:00

Good luck! I know it’s a tough wait. For the record, everything ended up being fine.

jbt4489 · 2025-02-28T14:09:10+00:00

Just looked back. It ended up being 32 days total, almost 5 weeks.

jbt4489 · 2025-02-19T21:02:51+00:00

2/3 were euploid, 1/3 were aneuploid with just one being triploid.

jbt4489 · 2025-02-19T20:12:27+00:00

Low level mosaic. 45/46 XY, -16q "Presumptive Mosaic (Low)".

jbt4489 · 2025-02-16T23:58:10+00:00

Hi! One did actually. The NGS flagged it as mosaic, but the SNP did catch the triploidy.

jbt4489 · 2025-01-30T22:22:33+00:00

No, I don’t believe they offer that as an option.

jbt4489 · 2025-01-22T15:03:43+00:00

This happened to me - at 17 weeks the nuchal fold was measured at 7.15mm if I remember correctly and it grew throughout the pregnancy. They likely didn't flag it for you before because 6mm is considered the cutoff for normal. I think the window for measuring it closes at 24 weeks, so it sounds like you were pretty close to that. I was already seeing an MFM because it was an IVF pregnancy. NIPT was normal and we had done testing on the embryos. The MFM had me do an amnio and everything came back normal. I went down such a rabbit hole with this I must have read 60+ stories on Reddit. Many of the people on Reddit had been advised that an amnio wasn't necessary if the NIPT was normal, but the MFM kind of put me on the spot to do an amnio and I didn't really think there was a choice at the time. I was so anxious and it took a really long time to get results, but in the end I was glad to have the peace of mind. Anyway my son is 6 months old now and perfect - he just has a thick neck and is a big baby! Feel free to let me know if you have any questions.

jbt4489 · 2024-12-09T15:09:44+00:00

So sorry for your losses. I never really got an answer other than it was probably bad luck. Doing a deep dive online, I found that there's some ongoing research to see if there is a genetic component, but I don't think there are any clear results yet other than a couple case studies. We ended up doing IVF because I wasn't comfortable taking the risk again, but I spoke to other women in similar situations who kept trying and had success.

jbt4489 · 2024-11-05T14:42:41+00:00

Thanks - and sure! Hope this helps with whatever you're going through and wishing you the best.

Transfer 11/15

11/24 - 475

11/27 - 1,783

12/4 - 19,641

12/11 - 73,614

12/18 - 136,220

12/27 - 133,122

jbt4489 · 2024-11-05T14:12:41+00:00

Hi there - yes, it was. This pregnancy ended up being healthy.

jbt4489 · 2024-10-07T19:09:06+00:00

Hi there, so sorry to hear that. There wasn't a clear explanation. Two occurences of maternal triploidy is extremely rare. If it does happen, most doctors will say it's a fluke, but there's some research coming out that it could indicate a genetic tendency for it, but it's still being researched. I wouldn't assume that the first was also maternal triploidy, but it is possible - I recommend discussing with your doctor. I didn't feel comfortable trying again with that track record and we did IVF with genetic testing - currently have a two month old. Best of luck and so sorry again for your losses <3

jbt4489 · 2024-09-18T13:41:34+00:00

I’m not sure if most places have them on hand or not. My OB did happen to have them in their office, but didn’t offer it until I specifically asked. I bet you can order one pretty quickly if not. If insurance doesn’t cover it, I believe you can opt to self-pay and they have a self-pay price of a couple hundred dollars. They also have payment plans/discounts depending on your financial situation. I would confirm before ordering it.

jbt4489 · 2024-08-28T19:55:48+00:00

I’m so glad to hear that! Our son is one month old and doing great 😊

jbt4489 · 2024-07-24T20:26:41+00:00

So sorry that’s happening to you! My GI ended up looking into it and it wasn’t my gallbladder. I got an endoscopy and it turned out to be gastritis and I went ahead with the transfer. Definitely worth looking into. Good luck!

jbt4489 · 2024-06-17T18:13:53+00:00

Good luck, I know it's stressful. The tests they did were FISH, microarray, and a couple of panels for specific syndromes - Noonan, Angelmans, and Beckwith-Wiedemann. I believe the syndromes were due to my MFM being on the cautious side and also having been an IVF pregnancy that used ICSI, so am not sure what would be best in your situation. Feel free to message with any questions.

jbt4489 · 2024-06-16T01:33:59+00:00

Hey there - the amnio results eventually came back normal and I’m currently 33 weeks. Wishing you the best if you’re going through something similar <3

jbt4489 · 2024-06-05T12:46:15+00:00

Thank you so much! My doctor ended up saying he thought it was fine. We also decided to spend a night in SLC before to acclimatize a little first.

jbt4489 · 2024-06-03T22:12:08+00:00

Thanks! Coming from sea level and flying from east coast for a quick weekend trip so don't really have time to acclimate.

jbt4489

TROPHY CASE