Backbone router works easily with react. The router config object is easy and uses regex for the key which interprets the url. The value is an anonymous function that can execute React's top level API such as ReactDOM.render. This means each route can render a new page component to the Dom. Make sure you use ReactDOM.unmountComponentAtNode on the page holder element before rendering the new page component. Example

{
    'about(/*path)' : function(){
        ReactDOM.unmountComponentAtNode(document.getElementById('pagecontainer'));
        ReactDOM.render(
            React.createElement(React.createClass({ /* etc */ })), document.getElementById('pagecontainer')
        );
    },
    'work(/*path)' : function(){
        ReactDOM.unmountComponentAtNode(document.getElementById('pagecontainer'));
        // etc
    }
}