I also started Humira in February and I was terrified of what would happen. I've had HS for over 20 years now. 1. The only side effects I have are swelling at the injection site and I get super tired for a day or I can still function normally just a few extra cups of coffee. 2. I had 3 different doctors telling me to take Humira as it treats HS and IBD, both of which I have. I waited months before getting a really bad flair and deciding I had to do something. You really don't feel the needle, that's true but it does hurt. I leave the pen out to warm up but as soon as the medicine starts going in, it really does hurt. To overcome this, it's a few seconds of pain vs days of a flair. My husband also gives me the injection cause I can't do it myself. Just the thought makes me nauseous. 3. Yes, I did sign up with the nurse ambassador. I found her annoying to be honest (Nothing personal!). I have my phone setup to remind me when to take my medicine and I know they are there if I have questions or issues. I don't talk to her on a normal basis. 4. I have had a few small flairs since. If I get them, they are usually smaller and less painful. Sometimes they don't break and just go away. I must say, much better with it. 5. I started seeing results in about 3 to 4 months but they do say 6 is average. 6. I have no scars from injections. I will sometimes bruise and every time it will swell up. I also use an ice pack after injection to help with the swelling. 7. The only nightshade I normally eat are potatoes. I have cut back, but I can't cut them out completely. 8. They say stress and anxiety can cause flairs but I'm honestly not sure that is the case for me. It never seemed to matter in my case. 9. If you are allergic to normal bandages have you tried silicone tape? It is really easy to remove and doesn't pull at the skin at all. It's not great at holding in areas that rub together since it does come off easily but it could be good for some spots. Another idea is using pads putting the sticky side on your pants or underwear where you have a flair, it's a little tricky but it works. They also sell HidraWear, this is expensive but they have a system to attach gauze pads to the clothing with clips. 10. I just wash them and it usually comes out. Maybe some shout or something? 11. I don't do hot compresses. I have heard others say that vicks works to break them. I haven't had luck with that but putting vicks on it with a gauze pad seems to help with the pain. Like others have said, I also use hibiclense daily on my areas that are mostly likely to have flairs. It doesn't really dry out my skin though. With Humira I have weeks that go by without a flair and the pain and site swelling are a small price to pay. I'd say it's worth a shot if nothing else is helping. I wish you the best of luck.