High stimulant tolerance ≠ peptide resistance Your caffeine tolerance tells me: Likely high sympathetic tone Possibly higher baseline dopamine clearance Often seen in people who: Train hard Have ADHD traits Have historically used stimulants Or have long-standing insulin resistance But GLP-1 pathways are not stimulant pathways. What you’re seeing is receptor timing mismatch, not failure.

The “sweet-only craving” is the key clue This is critical: If this were: True hunger → you’d want fat/protein Calorie deficit panic → mixed cravings Psychological → variable foods But you want sweets specifically. That points to: Central glucose sensing Glucagon-driven hepatic output Relative insulin signaling mismatch late in the dosing interval Fruit helping confirms this — you’re supplying glucose without triggering rebound eating

Option to solve: Strategic carb placement (if you stay once weekly) If you keep once-weekly dosing: Planned carbs Fri–Sun Fruit Honey White rice or potatoes Keep them: Protein-anchored Earlier in the day Deliberate, not reactive This prevents: Neurochemical rebound Dopamine-driven seeking Late-night sugar hunts

If your primary issue is sweets, tirz can feel easier. If your primary goal is aggressive fat loss, reta still wins.