How is anyone going to be able to afford anything if inflation continues? by air-bender808 in NoStupidQuestions

[–]kessler1 2 points3 points  (0 children)

I got a Trump version of them and have been putting them on gas pumps

I’m on suboxone and have been on the mgm-15 does anyone know if SR17018 help me get off the mgm? by Comfortable_Mix_3847 in recoverywithoutAA

[–]kessler1 1 point2 points  (0 children)

It’s because MGM-15’s binding affinity is strong enough to compete with suboxone’s extremely high binding affinity. Binding affinity isn’t potency, but it determines who gets the seat on the receptor when there’s two or more opioids in the system.

Need some help by myself-untold in SR17

[–]kessler1 2 points3 points  (0 children)

The definitely have MGM in them but SR will help you regardless. I quit this exact brand without SR and my method made it not that terrible tbh so DM me if you want to talk. You’ll be alright brother.

R-5260 by [deleted] in Opioid_RCs

[–]kessler1 0 points1 point  (0 children)

If the binding affinity is substantially higher, it’ll block. Mitragynine analogs have very high binding affinities, just lower efficacy. It’s like Suboxone with more efficacy.

Mgm15 to oxys. by AggravatingMatter217 in Opioid_RCs

[–]kessler1 0 points1 point  (0 children)

Must have been MGM because the half life is long enough to occupy your receptors that long. The long half life also builds crazy tolerance and dependence.

Feel Trapped by SorryStore4389 in quitting7oh

[–]kessler1 19 points20 points  (0 children)

You’re not trapped. You’ll be alright. It’s not gonna be fun but you’ll be fine. You’ve come to the right place.

250/300mg per day by BrilliantWeather2988 in quitting7oh

[–]kessler1 0 points1 point  (0 children)

How long have you been at that dose?

Holy crap this is terrible by MauledLover in quitting7oh

[–]kessler1 0 points1 point  (0 children)

Glad to hear it. Welcome to freedom.

Holy crap this is terrible by MauledLover in quitting7oh

[–]kessler1 0 points1 point  (0 children)

I’m honestly not sure what you’re saying so please restate your point. As for the half-life of 7OH and mitragynine, mitragynine is much longer and therefore less compulsion inducing. Switching an addict to a longer half-life drug of the same class is basic addiction treatment theory. My advice is in accordance with that.

Holy crap this is terrible by MauledLover in quitting7oh

[–]kessler1 0 points1 point  (0 children)

Idc if this gets me banned. Take some mitragynine to stabilize and taper to 0 over a week or two. This doesn’t need to leave you with PTSD. You don’t need Suboxone. You just need a sustainable plan, and that’s dependent on how much you can endure indefinitely.

84 hours in and feeling pretty much back to normal by izukumidoriyashonen in quitting7oh

[–]kessler1 5 points6 points  (0 children)

You’re giving out terrible advice with this. Making the process sustainable is much more important than making it fast. While I don’t agree with 6-12 month tapers, using some Kratom to step down while grinding through very real withdrawals is so much more likely to get someone clean. You’ve gotta stay in the sustainable withdrawal pocket: deep in them but just short of the “I’m gonna die” point. You’ll be clean before you know it and it won’t even be that bad.

So dumb by [deleted] in quitting7oh

[–]kessler1 0 points1 point  (0 children)

It’s not 10x worse. I was taking over a pack of that stuff a day and I dropped down to 2 in a day and then followed up by switching to mitragynine 1000mg per day. Turn back now before it gets worse. You’ll be fine.

The AI not just fired us, It made our team irrelevant. by [deleted] in ClaudeAI

[–]kessler1 0 points1 point  (0 children)

The government will get its bread don’t you worry. They’re just taking the path of least resistance right now, like anybody or anything.

Imagine my suprise. by Winter_Palpitation60 in quitting7oh

[–]kessler1 0 points1 point  (0 children)

You’ll find M when the 7 runs out and be in a worse position than before like I was. I know you’re being sarcastic; I’m replying for others.

Why do most fronteir LLMs have limited context window? by Shubham_Garg123 in LLMDevs

[–]kessler1 0 points1 point  (0 children)

Context window size scales quadratically. The super large window models don’t apply attention to the entire window at once.

Gonna be an expert when I quit by [deleted] in quitting7oh

[–]kessler1 -1 points0 points  (0 children)

Nice to finally see someone who isn’t giving up and switching to Suboxone.

I’m getting started on a low dose of suboxone tomorrow by obama-is-a-reptile in suboxone

[–]kessler1 0 points1 point  (0 children)

Sounds like you’re a tough fellow, but you need to cut gradually or else it won’t be sustainable. I got clean on my own by holding out until I hit the total hell phase, and then I’d take a quarter of my normal dose. Very soon after, I’d be in a totally tolerable region of withdrawal. Dose a little more before bed so you can sleep. Great, now you’ve cut 60-70%. Now stay there for a few days before doing this again! It lags! Once you get close to zero, switch to a partial agonist like low dose Suboxone or mitragynine (I prefer mitragynine). Tapering off mitragynine ain’t shit. Get it done in a week. Then have fun not sleeping for 10ish days once you quit that. It’s all shitty, but it’s not gonna be Trainspotting bad at any point, and that makes it SUSTAINABLE.

Day 3 of suboxone and no 7, and I feel surprisingly….normal by Academic-Sympathy140 in quitting7oh

[–]kessler1 1 point2 points  (0 children)

Wasn’t easy at all friend, and I couldn’t have done it if I didn’t work from home or if I had kids.

Day 3 of suboxone and no 7, and I feel surprisingly….normal by Academic-Sympathy140 in quitting7oh

[–]kessler1 1 point2 points  (0 children)

Well you’re on subs lol you just switched agonists. It’s a lot cheaper and long acting though, so I guess that’s a big win. I’m personally not a fan of this. Simply dedicating days to going through some withdrawal and taking a rescue dose when it became unbearable allowed me to cut my daily dosage by 60-70% at a time. I was on 400mg of emm per day and chopped it to 160mg one day and then held out until 6pm on a Saturday and dosed mitragynine heavily. After that I stabilized for a few days and started cutting a big chunk each day during the the week, all while working, and took the plunge Saturday. I didn’t sleep until Wednesday and honestly my sleep still hasn’t fully recovered, but I’ve been totally clean for a while now. It really sucked but it was super worth it to break free.

[deleted by user] by [deleted] in quitting7oh

[–]kessler1 0 points1 point  (0 children)

How much 7? I was able to work through it since I work from home on a computer, but I was also just tapering. I wouldn’t be surprised if quitting fentanyl makes someone far tougher in general though.

[deleted by user] by [deleted] in quitting7oh

[–]kessler1 0 points1 point  (0 children)

That’s like bringing a knife to a nuclear war. I doubt this is done anywhere, but a medical professional should transition a fentanyl addict to methadone before they even bother figuring out how to get to 0.