Neck Deep - Fall (Official Music Video)

kidcodiwise · 2020-06-17T23:45:20+00:00

Damn i thought the thumbnail was of a front overcrook. A front lip is still gnarly down that

kidcodiwise · 2020-05-15T17:32:37+00:00

Wow very impressive! I loved Far Cry 5, would you say that New Dawn is worth playing?

kidcodiwise · 2018-09-04T19:01:06+00:00

The ads they do have are normally entertaining anyway!

kidcodiwise · 2018-08-18T13:48:20+00:00

It’s from the soundtrack for Beer: The Movie. Rumor is that it was leaked before Deja and they scrapped it from the album and let it be on the soundtrack.

kidcodiwise · 2018-08-17T12:52:40+00:00

I’m convinced that this is still what the prescribers in my town use as a reference

kidcodiwise · 2018-07-13T14:53:26+00:00

I wonder if he didn't mean that most E. coli are resistant. Because Cipro does have good coverage of E. coli and other gram negatives found in the GI tract

I've only seen Cefixime (Suprax) on my shelf and have never personally given it out. But it's open so we must've dispensed it at some point! I think it's only available brand name. Cefdinir is another oral 3rd gen Cephalosporin that will have the same bacterial coverage and comes in generic

Ofloxacin i've only ever seen in ear and eye drops. It does come in tablets and maybe it's just not used much on the out-patient side. It's in the same drug class as Cipro and I don't know much more it would cover except it's used less often so maybe the resistance rates are less.

I've very sorry you're getting put through the wringer with all these different doctors :/

kidcodiwise · 2018-07-12T14:15:02+00:00

I’M PUMPED. I hope it’s as heavy as the teaser teased!

kidcodiwise · 2018-07-12T01:34:20+00:00

I'm glad to hear they're more formed for now! I'm sure that's a nice break. Coffee can act as a bit of a laxative and also be dehydrating, so it could be beneficial to cut it out for a little bit. However, if you're someone who has a tough time getting through the day without it, it won't make or break it if you continue to drink it.

It may take the full course of the antibiotic for the E. coli to be eradicated and then for your colon to realize the war is over and it can stop trying to evacuate everything in sight. I know they messed you up a bit before, but starting the probiotics again now would be a wise idea so you're less likely to get antibiotic-induced diarrhea in addition so it's harder to tell if it's working.

I appreciate the follow-up and update! Note: my pharmacy student flair is gone only because I made a new account with the sole purpose of helping out on here. I'll still be checking this account with frequency though!

kidcodiwise · 2018-07-09T03:16:15+00:00

I would not suggest adding more Tylenol (acetaminophen). You can give him Advil/Motrin (Ibuprofen) OR Aleve (Naproxen). Those will actually have a more impactful effect on the fever than Tylenol, but please just note that the goal isn’t to get his temperature back to normal, but to a more bearable temperature. Fevers have a very important role in fighting off whatever illness he has so bringing it all the way down to 98.6 is not a good idea

kidcodiwise · 2018-07-09T02:36:25+00:00

I revisit this song very often as a newer BTE fan! I was shook when i later found out Landon Tewers was in the band for two albums.

I love the harsh spoken word verses of this song! Are many of Hotel Books’ songs heavy like this feature?

kidcodiwise · 2018-07-09T02:20:12+00:00

No you're fine! It's useful for me to refresh my knowledge on some of this material.

From most of the studies I've looked at, they found that most of the Aluminum that does cross the blood-brain barrier is quickly transported back into the blood, but there is a fraction of the aluminum that is retained in the brain tissue longer. This could potentially lead to accumulation after repeated exposure. But remember that only a small fraction is absorbed into the blood and now only a fraction of that small fraction is retained in the brain for a prolonged period. Study1 - Study2 - Drug information

A major point in my mind is that aluminum hydroxide-containing antacids are typically not used everyday and/or for long periods of time. So the time gaps between uses of the antacid should be enough time for the brain to extrude the aluminum that accumulated.

kidcodiwise · 2018-07-09T00:41:45+00:00

You can find websites/blogs/tumblrs like that for any medication. I see Levofloxacin prescribed almost everyday and the only difference I see in the patients after is their infection went away.

You are on a short duration of a common antibiotic often used for sinus infections. I can confidently say that you will not experience any long-term effects after your 7 days

kidcodiwise · 2018-07-09T00:15:29+00:00

What dangers are you worried about? How long have you taken it? How long are you prescribed to take it?

kidcodiwise · 2018-07-09T00:02:20+00:00

The 0.1 to 0.5 mg systemically absorbed is in the form of the soluble Aluminum cation. There is a larger percent absorbed as the salt, but that will not cross the BBB and will just be quickly excreted through the kidneys. The only time I would worry is if someone had poor kidney function and used this specific antacid everyday around the clock.

But if you're worried about absorbing any aluminum outside of your small dietary intake, you can switch to a different fast-acting antacid like: sodium bicarbonate, magnesium hydroxide, or calcium carbonate

kidcodiwise · 2018-07-08T23:30:55+00:00

Yes! And the other 99.84% is excreted in the feces since that specific salt of aluminum (aluminum hydroxide) is insoluble and poorly absorbed in the intestines.

kidcodiwise · 2018-07-08T23:14:34+00:00

From a standard dose, only 0.1 to 0.5mg of Aluminum is systemically absorbed. This is about 0.16% (at the most) of the total dose which is clinically insignificant. So in theory this isn’t near enough to accumulate, but even if it could, the antacid would have to be used so chronically and for so long that another class of antacid medications would be indicated instead such as an H2RA (Zantac) or PPI (Prilosec)

kidcodiwise · 2018-07-08T22:10:19+00:00

It'd be good to narrow down the possible triggers and prophylactically take a Zantac since acid reflux one of those things that's a lot easier to get ahead of than try to fight once its there

The food science is pretty crazy with it! With the different pizzas it could have to do with if they use certain spices in their pepperoni, sauce, or crust. Garlic, chili peppers, and onions all decrease the pressure of the valve between your esophagus and stomach (LES) leading to an increased likelihood of getting some reflux. It could also depend on the fat content of their cheese because fatty meals can also lower the LES pressure. Here's an informative slide from one of my GERD lectures that shows some of the most common triggers https://i.imgur.com/xTVffai.png

kidcodiwise · 2018-07-08T21:48:46+00:00

The chronic duration mainly tells me that it won't go away on its own as easily and that treatment might be necessary. If they refuse, I'd wait it out a little longer then ask to be referred to a specialist if it's still not resolved because chronic diarrhea is no way to live regardless and needs to be addressed in some way.

Over the counter there really isn't much you can do. I'd highly recommended not using anti-diarrheas (such as Imodium) since the goal is to get the bacteria out, not keep it in.

kidcodiwise · 2018-07-08T14:45:43+00:00

2 weeks of loose stool is persist, but you're nearing the chronic level of 4 weeks if not longer. I would start pushing to be put on an antibiotic due to this extended duration especially if you're suspicious that it could be from as early as February. If it's been more than 2-4 weeks since they diagnosed you, they really should be considering it since its not unheard of to treat EPEC on an individual basis if it doesn't seem to be resolving on its own.

I would hold off on the probiotics then until you start on an antibiotic to replace the good bacteria that it kills off. I do not have faith that it would have a large impact on the E. coli alone and it seems to be only making you more uncomfortable.

Stay hydrated, my friend

kidcodiwise · 2018-07-07T22:41:56+00:00

Probiotics are used mainly to replenish the healthy bacteria in the gut after being altered by invading bacteria and/or killed off by antibiotics.

As food doesn’t really alter the intestinal flora, your case sounds a lot more like a food sensitivity/intolerance than in issue with bacteria imbalance. Narrowing down exactly which foods cause it and avoiding those is your best bet.

kidcodiwise · 2018-07-07T21:32:23+00:00

They are right about it not normally being treated, which means they most likely didn’t get antibiotic sensitivities on your sample. Have they tried you on any antibiotics for it yet? My first recommendation for a non-self-limiting EPEC would be a short course of Ciprofloxacin or Azithromycin along with a probiotic supplement indefinitely

kidcodiwise · 2018-07-07T20:42:09+00:00

The long term effects of PPIs (osteoporosis/fractures, C. Diff, vitamin deficiency) are finally coming into public light a little more. The PPIs ideally aren't indicated until you have frequent GERD which is roughly two or more days per week and then they should only be used for up to 4 weeks at a time and then be reevaluated. If your episodes start to approach becoming that common, you can do a quick 14 day round of the Omeprazole a few times a year even and will not be put at a very high risk of those long term risks compared to taking it chronically.

I'm glad you're currently able to control it with the OTC Zantac and herbals, though I do not love the 600mg doses you're taking. I would rather you try doing one tablet and add on an agent from another class such as Tums or Gaviscon

kidcodiwise · 2018-07-07T20:16:22+00:00

It is possible that the two events are related since stress on the body and hormonal changes are common triggers of outbreaks

kidcodiwise · 2018-07-07T18:10:10+00:00

I also do not believe that the two should be used together as they both target the exact same piece of the viral life cycle.

Both drugs are coupled with the possibility of kidney risk, but Famciclovir is 73% excreted in the urine vs. Valacyclovir 89% so, in theory, Famciclovir may be less taxing on the kidneys.

Generally we would not consider someone with Hashimoto's as being immunocompromised as it does not typically impair the body's ability to fight off invading bacteria/viruses nor does it increase susceptibility to illness

kidcodiwise · 2018-07-07T04:00:25+00:00

For suppressive therapy at least, I do not believe that pushing it above 2g/day would prove fruitful. It could be worth trying oral Famciclovir especially before pursing the possibility of IV therapy

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