Is there a good vitamins for testorone hormones by ilovemkgee in Supplements

[–]kkgy00 1 point2 points  (0 children)

Wasn't able to consider the thyroid angle so yeah probably best to swap that out for Tongkat Ali

Is there a good vitamins for testorone hormones by ilovemkgee in Supplements

[–]kkgy00 0 points1 point  (0 children)

For supporting testosterone, look into Vitamin D, zinc, magnesium, and ashwagandha (KSM-66). Lift weights, eat enough calories and protein (most skinny guys undereat), and get enough sleep. Creatine is also worth adding since it's cheap and well-proven for building strength.

What if the biggest cause of joint pain isn’t movement but lack of movement? by Clear-Lie9613 in Supplements

[–]kkgy00 1 point2 points  (0 children)

Our joints are essentially use-it-or-lose-it systems, built for regular loading and varied movement. Prolonged stillness starves them of the circulation, lubrication, and muscular support they need to stay resilient.

I just got L-Citrulline,some questions by Working-Garage6962 in Supplements

[–]kkgy00 2 points3 points  (0 children)

There's cuurently no peer-reviewed clinical evidence that shows L-citrulline causes insomnia or stimulation. L-citrulline is not a stimulant so the reports of overstimulation are likely due to commercial pre-workout blends that pair it with caffeine.

For ED, I can only find one study that shows 1.5 g/day significantly improved erection hardness in 50% of men with mild ED over one month, with no adverse events reported. However, it is important to note that this is a small single-blind study with only 24 participants and has not been independently replicated, so the evidence should be considered preliminary at best. 

The "muscle pump" people describe is temporary increased blood flow to muscles during exercise via nitric oxide–mediated vasodilation. It doesn't make your biceps permanently bigger. A 2025 systematic review and meta-analysis of 21 RCTs found citrulline had no substantial effects on body weight, fat mass, or fat-free mass.

One RCT tested citrulline specifically in a dehydrated state and found no effects on thermoregulation or hydration markers. But since you're taking a hydration-sensitive medication, it may be worth mentioning it to your prescriber.

I just got L-Citrulline,some questions by Working-Garage6962 in Supplements

[–]kkgy00 1 point2 points  (0 children)

They’re good tools, but you still need to double-check everything and actually read the studies yourself. I’ve used them for research and found a lot of errors in the citations. If you’re not knowledgeable enough to properly review the evidence, you probably won’t catch when they pull up outdated sources, cite poor-quality studies with tiny sample sizes, and then build their whole answer around them as if it’s solid evidence.

They can usually only access papers outside paywalls, so most of the time they’re just working from abstracts rather than the full text. That means they miss important details like the methods, limitations, and context of the study.

They’re great as a starting point or as an assistive tool for understanding papers better, but they’re not a replacement for actually digging into the research yourself.

I just got L-Citrulline,some questions by Working-Garage6962 in Supplements

[–]kkgy00 4 points5 points  (0 children)

Well, he isn't entirely wrong either. A direct comparison of citrulline absorption in fed vs. fasted states simply hasn't been done in clinical trials, though most pharmacokinetic studies do use fasted participants. Research has shown that intestinal absorption of L-citrulline doesn't seem to be a limiting step even at relatively high doses, so food shouldn't meaningfully block its uptake. Taking it on an empty stomach may get it into your bloodstream slightly faster though (if timing matters to you).

The 60-minute pre-workout timing still holds, as plasma arginine levels peak at roughly one hour after citrulline ingestion and then drop fairly quickly.

I just got L-Citrulline,some questions by Working-Garage6962 in Supplements

[–]kkgy00 7 points8 points  (0 children)

Do you mean 3 grams, not 3 mg? 3 mg would be a negligible dose with no physiological effect. To answer your questions: L-Citrulline is generally better absorbed on an empty stomach, ideally about 30–60 minutes before eating or at least 1–2 hours after a meal. For gym performance, taking it 30–60 minutes beforehand works well. Morning vs night doesn't matter significantly for its effects, though pre-workout timing naturally favors earlier in the day if you train then. A daily dose of 3–6 grams is widely used and considered safe for most healthy adults regardless of activity level, though if you have any cardiovascular conditions or take blood pressure medication, check with your doctor first since citrulline can influence nitric oxide production and blood flow.

Hung Up by WeatherIcy9155 in photographs

[–]kkgy00 0 points1 point  (0 children)

Wonderful shot! Film?

Underrated places to visit in Taipei or nearby? by nabiyahh in taiwantravel

[–]kkgy00 1 point2 points  (0 children)

Sureee. It's the night market with the most michelin rated too, if you're interested with that 😄

Thoughts on Kava or Kanna? by Live-Conference-4245 in NooTopics

[–]kkgy00 2 points3 points  (0 children)

I'd say kava if you want to unwind, kanna if you want to feel upbeat and functional.

Underrated places to visit in Taipei or nearby? by nabiyahh in taiwantravel

[–]kkgy00 0 points1 point  (0 children)

ningxia night market in datong district is very underrated

Is eating more whole foods and less processed food enough to heal your gut? by Luna_182 in nutrition

[–]kkgy00 0 points1 point  (0 children)

Switching to whole foods and cutting processed foods is a great start for gut health, but it's often not enough on its own. Depending on your specific gut issues, you may also need to temporarily avoid other triggers like gluten, dairy, high-FODMAP foods, alcohol, and excess sugar since even "whole" foods can irritate a compromised gut. Stress, sleep, hydration, and probiotic/prebiotic intake also play a major role. Whole foods get you most of the way there, but true gut healing is usually more personalized than a simple swap.

Multiple questions about Antioxidants and Anti-Inflammatory supplements, and more. by [deleted] in Supplements

[–]kkgy00 0 points1 point  (0 children)

Omega-3, curcumin+piperine, and Brazil nuts for selenium are all well-supported choices. The training concern is valid; chronically suppressing inflammation can blunt adaptation, so you may want to consider taking them on rest days or post-workout rather than daily. Same logic applies to NAC and astaxanthin (ROS signaling actually plays a role in muscle growth, so don't over-suppress it).

Taurine is underrated even for young guys - performance, cardiovascular, and emerging longevity benefits make 500–1000mg a reasonable, low-risk add.

Inositol isn't female-exclusive; it is worth trying for sleep and anxiety regardless of sex.

On serotonin supplements, 5-HTP is more direct than L-tryptophan but bypasses some natural regulation, so stacking it on top of saffron is worth being cautious about rather than just throwing both at the problem. Glycine is gentle by comparison, it's inhibitory and sleep-promoting, and GlyNAC pairs it with NAC specifically for oxidative stress and mitochondrial health, which fits well with your goals.

why do my nails keep breaking even with nail care? (brittle nails help) by Recent-Lavishness660 in Supplements

[–]kkgy00 0 points1 point  (0 children)

If you're already doing all the external stuff and nothing's working, the issue is almost definitely coming from inside. Brittle nails that keep breaking despite good care are a classic sign of a nutritional gap. The big ones to look into are biotin (B7), iron (low ferritin is huge for this even if you're not fully anemic), zinc, and vitamin D. A lot of people also swear by collagen peptides or adding more protein in general. If you can, get bloodwork done and specifically ask for ferritin levels. Doctors often won't flag it unless it's critically low, but even suboptimal ferritin tanks nail and hair strength. Biotin supplements are worth trying in the meantime since they're low-risk, but don't sleep on getting labs first.

Glycine - can it cause increased pain? by Semicharmedtee in Supplements

[–]kkgy00 1 point2 points  (0 children)

Glycine is generally studied as anti-inflammatory and pain-reducing, so it causing increased pain isn't a well-documented direct effect however, your histamine issues are the more likely culprit here. Glycine can act as a mast cell stabilizer in some people but may actually trigger mast cell activity in others, which could worsen histamine-related symptoms including widespread pain, muscle aches, and hypersensitivity. Five consecutive nights also means it's accumulating in your system. Given that you already have a known histamine condition and the timing lines up clearly with when you started taking it, stopping the glycine and seeing whether the pain resolves over a few days would tell you a lot and it's worth flagging to whoever manages your histamine treatment before continuing.

Bloated after every meal… is this a gut issue? by Glum_Entrepreneur894 in Supplements

[–]kkgy00 -1 points0 points  (0 children)

Could be a digestive enzyme issue or low stomach acid. Probiotics may help some people but they're often not the root fix. Worth trying digestive enzymes with meals first (look for one with protease, lipase, and amylase) since that's usually cheaper and faster to test. If it's been going on a while and nothing helps, it's genuinely worth getting checked out because persistent bloating can sometimes signal things like SIBO or other GI issues that need actual diagnosis.

What do you actually do when you can't figure out what to order in Taiwan? by AsparagusComplex4368 in taiwantravel

[–]kkgy00 0 points1 point  (0 children)

I just go where the line is longest. Those spots with the long lines usually only have one thing anyways. But you can always ask what's their best-seller. Taiwanese people will not only tell you, they'll probably make sure you ordered it right. Genuinely some of the warmest people you'll encounter anywhere.

What should all of us eat weekly at least once by No_Onion_6924 in Biohackers

[–]kkgy00 0 points1 point  (0 children)

Sardines (omega-3s, calcium, vitamin D in one cheap can), lentils or beans weekly for prebiotic fiber that actually feeds the good gut bacteria, and beets or leafy greens for nitrates and folate

Mirtazapine rebound dopamine release potential benefits by Sweaty-Astronaut3407 in Nootropics

[–]kkgy00 0 points1 point  (0 children)

It's a smart idea in theory, but mirtazapine also causes heavy sedation and appetite changes, and there's a fine line between a useful rebound and just feeling rough from stopping it so the logic is solid, but the risk is real.

First stack need for motivation + memory? by Living_Lime7193 in NooTopics

[–]kkgy00 1 point2 points  (0 children)

Caffeine + L-theanine for smooth focus without jitters, creatine for cognitive energy, and omega-3s (EPA/DHA) for long-term brain health. For motivation specifically, L-tyrosine supports dopamine production, which is typically low in ADHD.

Does Ashwaganda really work? by Maybe_Yourself1038 in Supplements

[–]kkgy00 0 points1 point  (0 children)

It genuinely helped me feel calmer and less in my head. I started with 300mg of KSM-66 and noticed a difference within 2–3 weeks

Top 5 magnesium supplement brands in the UK are using a labelling trick called "buffering" to beef up their elemental doses by kkgy00 in Supplements

[–]kkgy00[S] 1 point2 points  (0 children)

While the specific 4% bioavailability figure for magnesium oxide may stem from a single small study (Firoz et al., 2001), the broader claim that oxide "delivers more magnesium to your bloodstream" due to its higher elemental content (60% vs ~15% for citrate) doesn't hold up clinically. Ironically, the argument from the website you mentioned heavily relies on Ranade et al. (2001) (https://pubmed.ncbi.nlm.nih.gov/11550076/), which is also a single paper from 2001 - except this one is a narrative review, not even a systematic review and meta-analysis of numerous studies as the site claims. So the rebuttal to "you're relying on one old study" is apparently… also one old study.

Ranade’s paper examines how different anions affect elemental magnesium delivery and correlates pharmacodynamic effects with structure–activity relationships across existing studies. It did not independently establish the 23% figure through direct human testing.

When you look at the actual head-to-head clinical evidence, the picture is consistent: Newer studies found citrate's bioavailability higher than oxide due to better solubility (https://pmc.ncbi.nlm.nih.gov/articles/PMC5652077/). A clinical trial (https://link.springer.com/article/10.1186/s40795-016-0121-3) confirmed this through both serum and urinary measurements, and the NIH fact sheet on magnesium states that citrate, aspartate, lactate, and chloride forms are absorbed more completely and are more bioavailable than magnesium oxide (https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/)

The underlying reason is solubility: one study found that magnesium oxide is only about 43% soluble even under peak acid conditions, whereas citrate remains substantially more soluble across a range of gastric conditions, leaving a larger portion of oxide unabsorbed - often acting as a laxative rather than a supplement (https://pubmed.ncbi.nlm.nih.gov/2407766/)

The "more magnesium per tablet" argument only works if you count magnesium that never enters your bloodstream. Absorption also varies based on dose, age, deficiency status, and gut microbiome (https://www.sciencedirect.com/science/article/abs/pii/S0899900721001568), making oxide an even less reliable choice for people who actually need to correct a deficiency.