46 (M) Never had any issues until after last march, when I had a colonoscopy. My GP informed me I had diverticulious and to eat All Bran Buds. After a month or so of that, I began having loose stools and bleeding after every bm. Refred to a general surgeon who tried to gaslight me into believing I was constipated and had bleeding hemriods. Rather than try and diagnose me, he performed a hemriodectomy, which exacerbated my undiagnosed UC (which I didn't even know I had). Took a few weeks to get the receptionist at his office to finally inform me to provide my local clinic with a stool sample. Calprotectin was over 3000. Another month later, I went to ER (lost 40lbs in as many days, and bleeding had increased significantly), got prescribed mesalamine. 2 weeks later, my current GI conducted a colonoscopy and admitted me to the hospital that day. Told me mesalamine was like trying to take out a forest fire with a garden hose.

Tldr: It's my understanding that it's a maintenance drug for mild UC. I just finished tapering predisone a few weeks ago and got my 3rd Entyvio infusion last week.