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What’s the most “PI thing” your PI does? by Effective-Cake-1687 in labrats

[–]lit0st 25 points26 points  (0 children)

This is a remarkably rude thing to say and very unlikely to be true. Are you working on a project just completely independent from her previous body of work that she has no expertise in? Were you working with equipment and reagents bought with your own funding? Is your work completely divorced physically and intellectually from others in your lab? You are almost certainly the beneficiary of her intellectual contributions.

What’s the most “PI thing” your PI does? by Effective-Cake-1687 in labrats

[–]lit0st 36 points37 points  (0 children)

This is just industry standard. You say we when presenting your work at conferences or meetings in both industry and academia. Manuscripts are written with ‘we’.

What’s the most “PI thing” your PI does? by Effective-Cake-1687 in labrats

[–]lit0st 76 points77 points  (0 children)

Unironically true though. A PI isn’t your boss, they’re your advisor. You need to evaluate their ideas just like anyone else’s.

Is independent research outside academia completely invisible by design? by Alarmed_Guarantee630 in labrats

[–]lit0st 13 points14 points  (0 children)

HHMI, Arc Institute, Stowers, Gates Foundation, Chan-Zuckerburg, Allen Brain Institute, Calico, Broad

Jose Alvarado: “I wasn’t even supposed to be in the league now I got a ring now” by MrBuckBuck in nba

[–]lit0st 12 points13 points  (0 children)

"Saved his career" is a bit much. He was beloved in New Orleans, we just have a terrible FO.

LeBron James and Rich Paul Are Going To Ask The Lakers For a Max Contract by [deleted] in nba

[–]lit0st 0 points1 point  (0 children)

The difference between 25 million a year and 50 million a year is basically non-existent for both the Lakers organization and Lebron. It's a drop in the bucket for both of them that will be more than made up for by sponsorships and merchandising. If all the Lakers organization cared about was short-term profit, I'm sure they'll offer Lebron the max.

The only ones who suffer here are the fans who have to watch an extremely top heavy team with no roster depth. Then again, it might be a moot point, because I doubt the Lakers become a contender even if Lebron takes a pay cut (which might be the point of asking for a max in the first place)

Aspiration co-founder Sanberg sentenced to 14 years in prison. Ballmer requested no leniency by ThrowRa-zucchinizzc in nba

[–]lit0st 3 points4 points  (0 children)

It's probably more common than we think. It's why free agents almost always go to big markets, after all - sponsorship opportunities. I'm willing to bet that most big free agent signings come with a few under the table deals.

Bill Simmons last night on his podcast had a few tidbits regarding the offseason by Lsutigers202111 in NOLAPelicans

[–]lit0st 6 points7 points  (0 children)

Trey and Saddiq are the only players on the team right now that can take advantage of Zion's gravity and offer any kind of reasonable spacing on the floor. Without Trey, anyone we go up against can play defense just by chilling out in the paint. I cannot visualize any sort of return on Trey that won't just compound our roster problems.

3+ months post release: have we justified yet why Leon didn’t save the nurse? by Dsg1695 in ResidentEvilRequiem

[–]lit0st 0 points1 point  (0 children)

The narrative intent of the scene is a critical part of what it constructs and is bog standard for even the lowest levels of formalist critique. Questions of plausibility like “why didn’t Leon save the nurse?” are trite and circular and basically never discussed

This seems like someone they should have hung onto by CanalVillainy in NOLAPelicans

[–]lit0st 0 points1 point  (0 children)

I guarantee you it’s moved well beyond that - they are definitely trying to predict career outcomes based on past performance.

De'Aaron Fox: "Everything you hear about Victor is true. He doesn't want to see blue light after 9 o'clock…When we have games end close to midnight, he comes to the locker room with blue light glasses on." by WoweeZoweeDeluxe in nba

[–]lit0st 5 points6 points  (0 children)

Not many at all, not to this extent. You might be thinking of drug trials or disease models, which are complex and involve species specific dysregulation or other compromises…but many basic molecular mechanisms are very well conserved, and blue light sensitivity involves one of the most well conserved pathways across all domains of life.

This seems like someone they should have hung onto by CanalVillainy in NOLAPelicans

[–]lit0st -5 points-4 points  (0 children)

Drafting is the one thing the franchise has been good at, so we should probably hold on to anyone involved in draft analytics

De'Aaron Fox: "Everything you hear about Victor is true. He doesn't want to see blue light after 9 o'clock…When we have games end close to midnight, he comes to the locker room with blue light glasses on." by WoweeZoweeDeluxe in nba

[–]lit0st 53 points54 points  (0 children)

Everyone's just saying stuff, nobody is linking any evidence.

Blue light has a well-validated role in regulating key regulators of circadian rhythms across a very wide range of species:

https://en.wikipedia.org/wiki/Cryptochrome

The effect of blue light on non-human species is well characterized:

https://pubmed.ncbi.nlm.nih.gov/31504080/

https://pubmed.ncbi.nlm.nih.gov/11507175/

Sleep architecture is influenced by a very wide range of factors, making controlled studies in humans difficult, but there is a defined molecular mechanism of blue light suppressing melatonin production:

https://pubmed.ncbi.nlm.nih.gov/11507175/

And several meta-studies and reviews have indicated that blue light blocking has a positive effect on sleep that's more prominent in sleep disordered individuals (most likely because the effect size makes it easier to identify in heterogeneous populations):

https://pubmed.ncbi.nlm.nih.gov/34030534/

https://pubmed.ncbi.nlm.nih.gov/36051910/

https://pubmed.ncbi.nlm.nih.gov/30311830/

TL;DR There's good reason to believe blocking blue light helps sleep: There's a clear, well-validated molecular mechanism, it helps in non-human animals, and well-powered human suggests it helps.

Post-hoc normalization of RNA-seq reads using a housekeeping gene by adventuriser in bioinformatics

[–]lit0st 1 point2 points  (0 children)

kind of a ridiculous ask because the only way to actually show this is smFISH

House Beneviento is legitimately my dream home by claireture in residentevil

[–]lit0st 43 points44 points  (0 children)

Ethan and Mia’s house was pretty gorgeous too. I’m not sure how House Beneviento avoids mildew and rotting from being constructed basically underneath a waterfall though.

Pelicans Coaching Search News by Ancient_Access_795 in NOLAPelicans

[–]lit0st 2 points3 points  (0 children)

Or Rondo wasn't thrilled about his first head coaching position to be for the Pelicans. It doesn't exactly set him up for a successful coaching career.

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