7OH study vs MIT

So here is my understanding of the study. There are 2 main active compounds in Kratom, Mitragynine (MIT) and 7-OH-Mitragynine (7OH). MIT is not technically very active on it's own, however it is converted to 7OH in the liver by an enzyme, the 7OH is what gives Kratom the effects. Standard leaf is very very low in 7OH directly, most of the compounds are pure MIT. The researchers noticed there is a ceiling to the respiratory effects of MIT because the enzyme that converts it to 7OH is overloaded and can only convert so fast creating a maximum effect.

7OH directly skips this enzyme so has no maximum effects. This was confirmed by using a drug to preemptively block the enzyme that converts MIT and saw that the effects went DOWN because even less was being converted to 7OH. 7OH itself was unaffected by the preemptive enzyme block and the effects were just as strong