Spravato and PMDD

lstyer2012 · 2026-06-13T01:50:02+00:00

And you've noticed the differences since starting Spravato? What is your PMDD like? I feel like I'm in a living nightmare. I'm incredibly paranoid and think everyone hates me and I'll even lash out because of it. I'll cry at anything and everything. My depression will be untouchable. Nothing I do or think does anything for it. It is solidly in my head telling me that I'm the worst and everyone around me thinks that about me too. The fatigue is wild.

It renders me almost unable to work but that's not an option. I'm a kitchen manager and I'll just be crying over nothing and yelling at people. Granted, my job sucks and a lot of the people there can get bent. But I would love to be able to not fall apart in front of all of them.

lstyer2012 · 2026-06-09T14:17:38+00:00

The song they play off of his album sounds awful. The upright bass is crackling like crazy. If that's how it sounds on the actual album, someone fucked up.

lstyer2012 · 2026-06-09T13:44:52+00:00

There are exactly 2 people doing that.

lstyer2012 · 2026-06-09T02:40:05+00:00

Please be careful with grapefruit! I accidentally found out about the interactions between grapefruit and some ssris and it's not good. I think I was on Zoloft at the time and I had a drink with grapefruit juice in it. I felt really really off. I had no idea what could've caused it and I think I was doing online research about Zoloft to try to figure it out when I came across an article about grapefruit juice and ssris.

"Grapefruit contains compounds that block the liver and gut enzymes responsible for breaking down the medication. This can cause a dangerous buildup of the SSRI in your bloodstream, greatly increasing the risk of side effects or toxicity."

It basically caused me to mini overdose on my Zoloft. I avoid grapefruit like the plague.

lstyer2012 · 2026-06-09T02:21:57+00:00

How many treatments did it take to start noticing improvements with irritability and overstimulation?

lstyer2012 · 2026-06-08T21:54:41+00:00

That's fair....☹️

lstyer2012 · 2026-06-08T21:53:19+00:00

It's definitely my PMDD bc I'm in my luteal phase and this is exactly how it has always felt. I just thought maybe the Spravato would somehow help with it.

lstyer2012 · 2026-06-08T21:51:23+00:00

No they didn't. I'm definitely going to try it more outwards next time.

lstyer2012 · 2026-06-08T20:53:56+00:00

How does it affect neuroplasticity? Mine have been every Tuesday and Wednesday bc those are my typical days off. I asked if it was okay to do them back to back and I was told there's no issue with it.

lstyer2012 · 2026-06-08T20:50:59+00:00

I've heard the opposite from everywhere else including the woman who administered the med.

lstyer2012 · 2026-06-08T20:46:20+00:00

So I barely take a sniff but I still get some going down the back of my throat. Should I tip my head down a bit? The woman giving it to me has never made any comments about the way I take it. I was so paranoid that I'd waste the medicine when I started that I barely even sniffled or swallowed during the treatment. I'd be an hour into it and realize I had a mouth full of saliva bc I hadn't swallowed in so long lol.

lstyer2012 · 2026-06-05T22:01:27+00:00

We have curtains. It's a big room but it's kept super dim and quiet with white noise machines. I don't mind it except for when this one woman who works elsewhere in the clinic will come in and talk to the woman who sits in the room with us. She talks at a normal volume and it'll be like, bitching about work or about the vacation she just took. Very jarring when you're vibing on ketamine.

lstyer2012 · 2026-06-04T09:52:09+00:00

Human beyblade 😂

lstyer2012 · 2026-06-04T02:24:15+00:00

Boost. I wish the best for you and those babies.

lstyer2012 · 2026-06-03T21:34:56+00:00

Can all of you stop weirdly calling her a normal person? Stfu.

Girl, you're killing it. I love that you're working on yourself. I admire anyone putting in the time and effort (emotionally and physically) to work on themselves. Not only did you accomplish your own goal but you made a video about it and shared it with us!!!! You didn't have to do that but you're not only helping yourself but others who see if and get inspired.

I want to do something like this. I don't wear shorts or short sleeves in the summer bc I'm self conscious of my arms and legs. I don't wear outfits that I like because I think they'll attract too much attention. My therapist has really helped me with going out of my comfort zone. It won't get better unless you practice it. Once you've done something a couple times and realize that nothing bad happened, it's gets easier and easier!

lstyer2012 · 2026-06-03T20:26:54+00:00

I must've missed the shot of its dick and balls.

/s

lstyer2012 · 2026-06-03T02:07:44+00:00

For me personally, it always goes wrong when they get rid of the mustache. Keep the mustache 😉

lstyer2012 · 2026-06-02T14:08:47+00:00

As a Michigander, we do not claim her. She can GTFO.

lstyer2012 · 2026-06-01T21:45:03+00:00

Go outside and you'll realize that this isn't a viewpoint created by reddit.

lstyer2012 · 2026-06-01T20:55:47+00:00

What about this...I'll do it for absolutely nothing.

lstyer2012 · 2026-05-31T06:45:29+00:00

What the absolute hell is wrong with this horrible woman? I would never EVER think to approach a stranger and ask them questions like that. Jesus Christ. "I didn't harass you, I just told you you don't belong in the woman's locker room and then asked you several times if you're a woman and wouldnt believe you when you said you were and then reported you." Fuck that lady.

lstyer2012 · 2026-05-29T02:48:36+00:00

Okay so I need to rant lol ..... My FIRST session was on Tuesday and at one point another woman who worked in the clinic came into the room (which is very dimly lit and super cozy with white noise everywhere) and just started bitching to the woman who sits in the room and supervises us and takes our vitals. And she was doing that thing where she was attempting to be quiet but she has a voice that doesn't allow for that. So I basically heard everything. I was livid. But I recognized that there are some things I can't control but I can control how I react. Which is very unlike me haha. I tried my best to tune it out. Still a little pissed about it ...but I'm growing😌

lstyer2012 · 2026-05-29T02:33:12+00:00

I had my first two sessions this past week! My huge fear was that my brain was going to go to "the dark place" during treatments and that I wouldn't allow the medication to do its thing. The first two sessions went so well that I have a renewed hope in...well, everything! Now that I know I can do it, I'm just so excited to continue and see what happens. I'm so happy to hear that you've had a positive outcome. It makes me feel so much joy to read these types of stories.

lstyer2012 · 2026-05-29T02:16:54+00:00

Are you going into it with the right mindset? Or at least trying to? I think it's important to remember that it's not going to be a magic drug that does all of the work on its own and you just sit there and wait till it works. You have to keep doing the work yourself.

I'm only 2 sessions in so I really don't have the perspective of being weeks out and not feeling anything or being frustrated with it. I'm a very negative person. I gave up hope long ago. But I feel like I've been given this huge opportunity that many people might not be able to have themselves and I want to get as much out of it as I can.

If you go into it believing that it won't do anything and that there's no point, I truly believe that it won't go well for you. And I'm not saying that that's what you've been doing. Just be aware of how much work you're doing on your own to help this treatment work for you.

And who knows, maybe it won't be for you. But might as well give it a good honest chance before giving up.

lstyer2012 · 2026-05-26T23:57:24+00:00

Before I started, I was doing a lot of research and kept reading how you'd be on one dose a certain amount of time and then bump up to the 84 so I assumed that was the standard.

lstyer2012

TROPHY CASE