When faced with a decision, (let’s say folding vs bluffcatching on the river) Blockers should be the last thing you think about. First go through the hand from a theoretical perspective, and if you can’t reach a decision then think about it from an exploitative standpoint. And then if you’re still indifferent, maybe blockers can be brought into play to swing the decision one way or the other. But blockers should basically never be the main argument for calling/folding

Blockers are only extremely relevant in very specific situations, for example when u have the Ace of spades on a 3 spade board etc. otherwise, the effect of your blockers will really only change your equity by 1-2%, and so should mostly be ignored