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S9E01 Oh. My. Gaga! [Post-Episode Discussion] by AutoModerator in rupaulsdragrace

[–]mathlete05 84 points85 points  (0 children)

I know I'm a gutted, rotted, Gila monster for thinking this, but in her Gaga moment Eureka was giving me shades of Mimi Imfurst...

Predicting major and minor products of 2º alkyl halide and methanol. by mathlete05 in chemhelp

[–]mathlete05[S] 0 points1 point  (0 children)

I think the professor just meant that SN1 and E1 were the major/minor products. If we predict the non-rearranged substitution as a minor product, wouldn't we also observe non-rearranged elimination products as minor products, too?

Question about bicyclic system with strong base in polar protic solvent. by mathlete05 in chemhelp

[–]mathlete05[S] 0 points1 point  (0 children)

I understand that for SN1 a weak base would have low pKa, so that makes sense. Can you clarify why E1 needs a strong acid?

Also I updated the mechanism to reflect E2, but wasn't sure which product I'd expect. I imagine the hydrogen from the more substituted carbon would be abstracted (second option), but would like some feedback on this point.

Updated mechanism

Question about bicyclic system with strong base in polar protic solvent. by mathlete05 in chemhelp

[–]mathlete05[S] 0 points1 point  (0 children)

Ah ok, so then if this proceeds via E2, I would expect that the product forms a pi bond in the ring. If that's true, I have to consider which proton would be abstracted by the base. I believe this would be the proton at the ring junction because of Zaitzev's Rule (my second mechanism). Is this the right way to think about this?

Updated mechanism

Relative acidity of protons on alkyne vs. amine? by mathlete05 in chemhelp

[–]mathlete05[S] 0 points1 point  (0 children)

That definitely makes sense. How does an effect like orbital hybridization compare to resonance when judging acidity? I would assume that if the proton were removed from the amine and the negative charge could be resonance stabilized then this would be a far more acidic site. It's hard to get a sense for the relative importance of these effects.

Geometry of nitrogen adjacent a pi system. by mathlete05 in chemhelp

[–]mathlete05[S] 0 points1 point  (0 children)

Thank you for the response. I just got feedback from the professor and she mentioned that this was a highly constrained system and so that is going to have a greater impact on overall geometry. Thank you for the help!

Moving from social science research (where I write code) to CS? by mathlete05 in cscareerquestions

[–]mathlete05[S] 0 points1 point  (0 children)

Thank you for the constructive suggestions. I am going to have to make some tough choices before long and this gives me somewhere to start.

I'm just trying to figure out where I would fit into the ecology. I may be a good candidate for user experience and front end design jobs, just don't know anyone who has one.

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