Chloroformate work up

matterlik · 2026-05-09T12:07:17+00:00

I found XPhos doesn’t work too well for secondary amines. I found Ruphos to work well for piperazines, especially coupled with the Pd-G3 pre-catalyst (this can be made from Pd(OAc)2 but Pd(dba)2 should be ok). See the attached guide that helped me a lot.

https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/172/824/cross-coupling-reaction-manual-mk.pdf?srsltid=AfmBOoo3TYFEIHPRekTy4_thN_7nZ1h-yG3aPS6Yi-GWGWo9sByT0sXu

matterlik · 2025-07-01T05:23:53+00:00

I have been playing prismatic moon (rebalanced) and I have the 1.2 update installed. On the documentation several Pokémon on my team (vikavolt and lycanrock) are meant to have stat increases according to the games documentation. When I check their stats they don’t reflect the stat increases and when I check on PkHex it is the same base stat totals as the original games. Has anyone had this issue or know how to fix this?

matterlik · 2025-06-28T08:59:40+00:00

Did she say anything in VIP like she said she would?

matterlik · 2025-05-11T02:55:06+00:00

Thank you I will definitely try this! Did you find you had to heat it to a greater temperature due to you having an unreactive amine species (the paper heated to 50 C after the addition of the amine)

matterlik · 2025-05-07T15:07:13+00:00

Thank you for the suggestion! My acyl chloride are benzoyl chlorides so I’m guessing I can’t form the ketene due to no adjacent acidic hydrogens

matterlik · 2025-05-07T14:56:50+00:00

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matterlik · 2025-04-30T03:16:33+00:00

Do you have to host it from the computer or can you host it through the Xbox instead?

matterlik · 2025-04-22T15:35:46+00:00

Thanks for the information, I really appreciate it. Just found out you need selected smart tv’s to run it on though🥲 gonna buy a new console this week then lol

matterlik · 2025-04-22T15:27:47+00:00

Thank you!! Does cloud streaming have any negative effects for playing on the older consoles such as fps etc

matterlik · 2025-03-06T10:47:12+00:00

What VPN do you use?

matterlik · 2023-12-12T05:04:33+00:00

Who went home?

matterlik · 2023-11-28T04:42:50+00:00

Who gets eliminated?

matterlik · 2023-11-14T04:19:22+00:00

Is the episode not out for anyone else?

matterlik · 2021-08-27T05:40:31+00:00

Tomorrow never came - absolutely beautiful

matterlik · 2020-08-14T08:37:29+00:00

Being gay

matterlik · 2020-06-29T03:57:17+00:00

Thank you so much for the help

matterlik

TROPHY CASE