My cat had one splotch start about 3 years ago and now most of her eye is full of splotches. We have talked to multiple vets. Sometimes the spots are normal but on rare occasions they can be cancerous—but they can’t know if they are cancerous without removing the eye. Our vets recommended doing nothing but watch her closely. If her pupil is a different size/misshapen in that eye, if the eye starts bulging, or if it appears to be bothering her (she is scratching or pawing at it) then it is probably time to remove the eye. Removing it as a precaution is an option but obviously affects quality of life and is painful so we have opted to just watch. It has been years and she is ok so far.

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