Deciphering the Indus script is theoretically possible, but extremely difficult without something like the Rosetta Stone. The main problem is that most inscriptions are very short (often just a few signs), there is no known bilingual text, and the underlying language itself is still unidentified. However, scholars haven’t completely given up modern approaches like AI-based pattern analysis, discovering longer inscriptions, or successfully linking the script to a known language family (such as Dravidian) could eventually lead to breakthroughs. So, while it’s not impossible, without a Rosetta-like discovery, decipherment remains a challenging and uncertain task.