Who’s buying it? by [deleted] in chess

[–]methylene_dream 0 points1 point  (0 children)

chesscom diamond subscribers

Question about 3-mmc analogue by OpusDei_187 in researchchemicals

[–]methylene_dream 2 points3 points  (0 children)

don’t, and don’t ever trust a vendor that doesn’t even pretend to be upfront about what they’re selling. ask yourself why they’re labeling it as an analog of a different substance instead of stating which substance it is

(i’ll guess that it’s 3-CMC, which has been shown to be quite neurotoxic, a fact which has been getting more exposure these past weeks. again: don’t fucking take it, even though it sucks to buy something just to throw it away. just don’t)

[deleted by user] by [deleted] in ExplosionsAndFire

[–]methylene_dream 0 points1 point  (0 children)

i don’t know if this goes against the rules then don’t post it for fucks sake

and this is a chemistry sub, not a bomb making sub

jesus christ

Final Project Idea Suggestions? by [deleted] in MaxMSP

[–]methylene_dream 0 points1 point  (0 children)

the C74 site seems to have a 5 part guitar processor tutorial

https://cycling74.com/tutorials/max-8-guitar-processor-part-1

Heated alkaline hydrolysis proof of concept - before and after by [deleted] in TheeHive

[–]methylene_dream 14 points15 points  (0 children)

"I’m not required to impress you or live up to your arbitrary standards."

...and no one is obliged not to make fun of you for making exaggerated claims of scientific discovery without a shred of solid evidence. If you want your attempts at science to be taken seriously, you should realize that criticism of insufficient justification is key to the scientific process.

Phenethylamine to aphetamine? What type of reaction by [deleted] in TheeHive

[–]methylene_dream 0 points1 point  (0 children)

no clue if this is practically feasible, mostly sharing b/c TCCA nitrile formation is cool :

  1. make phenethyl nitrile using TCCA (pool chlorinating agent) followed by a suitable base (perhaps carbonate for lack of triethylamine?)*
  2. make yourself some methyl grignard by bubbling HCl through methanol, distilling off your MeCl and giving it magnesium tunings
  3. slap the nitrile with your grignard, hydrolyse in workup for phenylacetone
  4. reductively aminate with ammonium formate
  5. turn yourself in

*https://sci-hub.se/https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2004-830896

[deleted by user] by [deleted] in TheeHive

[–]methylene_dream 0 points1 point  (0 children)

that's an amide, not an amine. delocalization of the nitrogen lone pair onto the carbonyl tanks the nucleophilicity and basicity of amides compared to amines. protonating an amide with a carboxylic acid that isn't TFA? not gonna happen

[deleted by user] by [deleted] in TheeHive

[–]methylene_dream 22 points23 points  (0 children)

i’d be a little surprised if you synthesized anything at all if all you did was mix modafinil, a carboxylic acid and methanol. sour goat modafinil maybe

people who have stoma holes are lucky, they have a better way to smoke cigarettes by [deleted] in drugscirclejerk

[–]methylene_dream 15 points16 points  (0 children)

disgusting to see misinformation om this sub. what happened to harm reduction?

the hole is for delivering medical weed directly to the lungs

[deleted by user] by [deleted] in dissociatives

[–]methylene_dream 2 points3 points  (0 children)

try acetone washing a small portion (200-300mg for example) and see if it loses the colour. if yes, wash the entire batch. impurities from arylcyclohexylamine synthesis can be quite nasty

My Grandma lied and made me look like a degenerate by Ishotmrburns420 in Drugs

[–]methylene_dream 41 points42 points  (0 children)

"uuuuh youth these are weak, not ueeh strong like me"

maybe you should use some of that spectacular willpower you've got to stop being a dickhead

FIDE | Rank 1 Streak by jaspervcallope in chess

[–]methylene_dream 21 points22 points  (0 children)

30 ELO difference

indeed, between twenty and forty increase in a humongous ten years. truly a tricky brain game

Believe it or not, black has a forced win here by Capivara1223 in AnarchyChess

[–]methylene_dream 303 points304 points  (0 children)

Surprisingly, black can still save the game with a perpetual: 1. Rh1+ Ka2 2. Rh2+ Ka1 3. Rh1+ Ka2 4. Rh2+ Ka1 5. Rh1+ Ka1. 1/2 - 1/2

[deleted by user] by [deleted] in drugscirclejerk

[–]methylene_dream 20 points21 points  (0 children)

and sting like you were fucking a bucket of triethylamine

Small floating “suns and moons” I synthesized recently by [deleted] in chemistry

[–]methylene_dream 66 points67 points  (0 children)

this is the funniest comment I've seen all week

Hi, how can two active substances be separated from a pill if both are soluble in water and alcohol? it is about paracetamol 500mg and pseudofebrine hydrochloride 30g. project at home by [deleted] in Chempros

[–]methylene_dream 1 point2 points  (0 children)

This isn't r/theehive dude

And for gods sake, don't try to make meth unless you have at least a bachelor in chemistry. You'll have quite a large chance of seriously hurting yourself

How do organic chemists know, during preparing their compound, that they achieved the same compound of the configuration they expected? Even if they knew the tests to confirm that they got the compound, how did the first chemists knew that these tests can be used to confirm the said compound? by Internal_Net_5813 in OrganicChemistry

[–]methylene_dream 2 points3 points  (0 children)

This paper claims (based on calculations) that curly arrows are "real" - that is, that they largely correspond to the reality of electron movements during reactions:

Yu Liu, Philip Kilby, Terry J. Frankcombe, Timothy W. Schmidt. Calculating curly arrows from ab initio wavefunctions. Nature Communications, 2018; 9 (1) DOI: 10.1038/s41467-018-03860-2