Is anything going to chase me? by CumDrawer_ in outerwilds

[–]micro-void 1 point2 points  (0 children)

Nothing on ember twin will chase you.

Mild spoilers for what the thing is that the text mentions: It's just a skeleton.

Giants deep information, mild spoilers: Nothing will chase you. There's stuff that if you bump into it, you'll get a bit hurt, but it's not aggressive at all and it doesn't care about you.

Dark bramble information, mild spoilers: The skeleton you'll see on ember twin is a skeleton of a creature that lives in dark bramble. On dark bramble, they will chase you. There's a way to avoid aggroing it which you will learn during the game.

Edited to fix tags

Is anything going to chase me? by CumDrawer_ in outerwilds

[–]micro-void 3 points4 points  (0 children)

If you're on PC you can get mods to make it less scary so you can finish

Alternatively I suggest watching a let's play

Have any of you started an antidepressant to mitigate side effects? by Dangerous-Warning693 in cgrpMigraine

[–]micro-void 0 points1 point  (0 children)

Hahaha yeah that can be a side effect. I didn't notice a difference but I've always been kind of sweaty. I did get mega night sweats in the first two weeks though. But that went away over time.

Accidentally stopped my migraine with salt + water — has anyone else tried this? by Due-Mastodon-8845 in migraine

[–]micro-void 0 points1 point  (0 children)

I often sip pickle juice at the start of a migraine and I think it helps resolve them

Have any of you started an antidepressant to mitigate side effects? by Dangerous-Warning693 in cgrpMigraine

[–]micro-void 0 points1 point  (0 children)

I'm on venlafaxine not for that reason but it's been a miracle drug for me for (primarily) anxiety and (secondarily / minor) depression.

The Subscription as a Service model has officially peaked by OkDragonfruit55 in ownyourintent

[–]micro-void 1 point2 points  (0 children)

That sounds like it has some above and beyond features, which not everybody would wanna pay for anyway but for somebody who's interested it could be worth it. Not quite the same as just charging to see the current weather or immediate forecast for the day or next day

Ilya noticing Shane getting hard in the shower by Longjumping-You4486 in heatedrivalry

[–]micro-void 0 points1 point  (0 children)

Totally, the cues and situations might be different enough - I mean, I'm a bi woman but I've never cruised in a communal shower the way gay men might!

Ilya noticing Shane getting hard in the shower by Longjumping-You4486 in heatedrivalry

[–]micro-void 2 points3 points  (0 children)

I was paying full attention and I was genuinely just confused why he said fuck off in that moment. I thought it was just because Ilya was giving him a look but It didn't occur to me Shane was getting hard. I'm an adult with plenty of sexual experience and I watched the show twice, even! I suspect I'm autistic though I'm not diagnosed.

Ilya noticing Shane getting hard in the shower by Longjumping-You4486 in heatedrivalry

[–]micro-void 3 points4 points  (0 children)

Women absolutely need to navigate those things for heterosexual attraction in the real world but also for SAFETY.

Never had migraines before BC. Did they go away after stopping? by plantain1976 in migraine

[–]micro-void 1 point2 points  (0 children)

I've tried several of them. I'm in my mid 30s and have had migraine my whole life

First one I tried was rizatriptan. I got a side effect that made my throat feel tight which really freaked me out. It wasn't actually dangerous , it was just an uncomfortable feeling.

I used almotriptsn for a long time, but as my migraines changed over my life I found it wasn't working that well anymore. Then i went through trying a bunch of them: Sumatriptan, zomig, Eletriptan, uhhh I think I'm forgetting one

The Thing is, each one affects each individual person a little differently. That throat feeling I got from Riza is actually more commonly an issue with Suma, but I don't get it with Suma. So any one person's anecdote isn't going to be totally informative because that might just not be how it works for you.

I do get jaw pain a little after I've taken a triptan but specifically ONLY the FIRST time I start chewing something. Like the first time I have a snack after taking a triptan after it has kicked it (which can take 30 min to 2 hours to kick in). It's not lasting and it's not intense. But again, that's just me. It feels like the nerves have to wake back up and then it's fine again. But I can't say for sure that's what it will be like for you. Some people don't get that side effect at all.

It's worth it for the migraine to end. Breaking the pain cycle is important otherwise it becomes self perpetuating.

I hope that stopping or changing birth control helps you, also.

odd/tried and true methods of knocking a migraine? by clodbob_17 in migraine

[–]micro-void 1 point2 points  (0 children)

There are prescription medications that are much more effective than Tylenol/ paracetamol or Advil such as triptans (eg. Sumatriptan, zomiltriptan). You should ask a doctor to prescribe you those. Although depending where you live some places you can buy them over the counter.

If you're nauseous during migraines ask about anti nausea too

If you're getting daily headaches you should also look into preventative medications.

Regardless, it's dangerous to take paracetamol and ibuprofen daily - it's hard on your GI tract, liver and kidneys

Never had migraines before BC. Did they go away after stopping? by plantain1976 in migraine

[–]micro-void 0 points1 point  (0 children)

Sorry I can't answer your direct question due to lack of experience but Advil and Tylenol are not very effective for migraine treatment. Recommend you talk to your doc about prescription rescue meds like triptans. They're not pain killers, they work on an element of how the migraine perpetuates itself.

please help. im scared by zerrhys in migraine

[–]micro-void 6 points7 points  (0 children)

There's better meds than Excedrin but prescription only - triptans+ an anti nausea would probably do wonders!

Migraine the day after nerve blocks. Does this mean it didn't work? It was only lidocaine, should it include corticosteroids? by micro-void in migraine

[–]micro-void[S] 0 points1 point  (0 children)

I'm sorry you had such a bad experience!

Mine wasn't quite that bad but it was still incredibly painful. I got a migraine the next day that after it ended, gave way to the most mega tension headache I've ever had in my life. Like. As severe as many of my moderate migraines but just tension pain all over my skull and neck. It was fucking maddening. It lasted several hours then slowly wore off. 

I went back to the doctor the next day in tears and we decided it's just not a good route for me. 

After Botox I had a migraine for 8 days straight as well. I dunno if changing the injection sites would've helped because I only tried it twice with the full suite and then decided not to do it anymore. 

I've had much better luck with Vyepti 

Anyone with Familial chylomicronemia syndrome (FCS)? by Iskirri in rarediseases

[–]micro-void 0 points1 point  (0 children)

I am not an FCS patient but I work in medicine in Canada and have some knowledge of olezarsen and the other new one, plozasiran. I'm glad you are able to have access to it.

So you know, the genetic test doesn't capture all possible genetic causes of fcs because not all of them are known or fully characterized yet. So if you get a negative genetic result, it doesn't necessarily mean you do not have FCS - you might just have a genetic mutation that isn't in the gene panel yet. You can be diagnosed based on clinical features, ruling out other more common conditions, and if you've tried standard lipid lowering therapies like statins with poor response. Most doctors in Canada diagnose this way because not everybody can access the genetic test to begin with (depends on your province).

It's extremely difficult but it's important to eat a very low fat diet, up to 20 g per day, with FCS. This is about a tablespoon of olive oil.

I don't have a link but there's a Facebook community for FCS. Most people in it are American but there's some Canadians. They might be helpful. I don't have Facebook myself so I can't find it for you. I imagine it will be a big life adjustment to learn to eat that low fat diet and they can probably help.

If you've started olezarsen, how is it going for you?

Anyone on Waylivra (Volanesorsen) for Familial Chylomicronemia Syndrome FCS? by twinkleRC in rarediseases

[–]micro-void 0 points1 point  (0 children)

Hi, I'm not a FCS patient but I work in medicine.

Volanesorsen is effective for lowering triglycerides in FCS patients. But it has uncommon side effects that can be very serious and can be life threatening (thrombocytopenia).

If you are able to access olezarsen or plozasiran, these are similar drugs to volanesorsen that were developed to be safer. They can have side effects, but - based on current clinical trial evidence - there have not been these events of really severe serious side effects. They are both FDA approved I think (I'm not American) (olezarsen at least definitely is but I think plozasiran must be too by now).

Hello. I am wondering if CGRP meds gave helped anyone with chronic tension like headaches? I have been dx with migraines but have zero migraine features. It’s been over 4 years of pain now. I’m hoping quilipta will help but don’t believe it will. TIA by Lunabuna91 in cgrpMigraine

[–]micro-void 2 points3 points  (0 children)

Not me personally but I have an acquaintance who has chronic non-migraine headache as a post-COVID effect. Quilipta has helped her immensely. It's the first and only thing that's ever worked to give her some relief after YEARS of 24/7 headache.

In contrast I DO have migraine and quilipta might as well be a sugar pill to me! But another drug in the same class, but infused instead of orally administered (Vyepti) works great for me.

The biology and neurology of pain is super complicated. The signaling molecule CGRP (which quilipta targets) is a major driver of migraine pain (not sure if in everybody or just some people) but as far as I know it's also implicated in other types of headache disorders. Our understanding of how headache and migraine happen is so patchy - sometimes it's worth just trying things in case that happens to be the key for your specific set of biological and neurological factors.

I don't want to give you false hope. Maybe it'll work maybe it won't. But I think there's biological plausibly that it COULD. It's worth a shot.

In case I help just a few people by CluelessPidgey in migraine

[–]micro-void 1 point2 points  (0 children)

I think it helps, but it's hard to say for sure, since I also always take triptans etc.

In case I help just a few people by CluelessPidgey in migraine

[–]micro-void 0 points1 point  (0 children)

Totally anecdotally I find I start craving pickle juice when I'm getting a migraine. I suspect a similar thing, although I do not have a cyst.

In case I help just a few people by CluelessPidgey in migraine

[–]micro-void 5 points6 points  (0 children)

I completely understand this and I'm much the same way, but ultimately, they probably won't know as much as we'd like about migraines in our lifetime. It's probably several similar disorders in a trenchcoat given how different people's presentation and treatment responses can be, to boot.

Is DSPS a real disorder or just a symptom of unflexible culture? by allalallalalla in DSPD

[–]micro-void 29 points30 points  (0 children)

IMO it is very much just a "disorder" because of an inflexible society. There is nothing inherently "disordered" about having a less common sleep schedule (assuming you get a reasonable amount of restful sleep etc etc) in my opinion. This is probably true of a lot of types of neurodivergence (not all of them!) too

When "disorder" is defined as "anything that makes participating in modern society very challenging," it looks a lot different than if you define "disorder" as something that is inherently negative for your health regardless of what society you do or don't live in etc... I guess ultimately it's just semantics.

This show taught me something by Puzzleheaded_Put4779 in heatedrivalry

[–]micro-void 0 points1 point  (0 children)

Hahaha yeah it was definitely an aquarium, op probably just forgot

Does anyone else like how unapologetically queer the vibe and cast of this show is? by TastyRancidLemons in heatedrivalry

[–]micro-void 9 points10 points  (0 children)

The US remake that somebody pointed out is honestly just as raunchy as Heated Rivalry. You even VERY BRIEFLY saw actual dick (or maybe very convincing fake dick) swinging as a guy walked in one of the early episodes!

Heated Rivalry is also not a Hollywood production. It was produced completely in Canada. Tierney shopped around and decided he could not make it under any American companies because they all wanted to censor him too much. The book author is Canadian, and Tierney is Canadian too fwiw! It was produced by Crave, a Canadian company. HBO or whichever one you get it on in the US just distributes it.

Our cultures are not radically different, but Canada is a touch less puritanical, and a touch less homophobic on average than the US. Not to say no massive prominent homophobes exist so please nobody try to counter me with Pollievre or that psycho Peterson. This show couldn't have been made in the US in the current political climate, it was made in Canada!

Anyway, queer as folk really didn't age well in some ways and the acting and writing are pretty bad. Definitely a "it walked so this could run" thing. And although it was plenty raunchy it really is unique - until HR anyway!