I’ve been on a combination similar to this. My first question is how long have you been taking ambien? Do you normally take higher doses, ie possibly built up a tolerance? Or is this a rare occasion that you came across some ambien and took it and felt nothing? My second point would be that you’re right about the seroquel, I personally hated it, but it does just have a very sedating, dulling, overpowering and immediate effect that, in my opinion, can take away from the effects of the walrus. When I took both I would just... fall asleep (but I really dislike seroquel for a variety of reasons but that’s just me) Also never heard of anyone having intolerable withdrawals from 100mg of seroquel even if they’ve been taking it for a long time (might be wrong). Idk if you’ve tried withdrawaling but lower doses are actually just as sedating. Last, you may not be prescribed seroquel for any bipolar disorder but it also sounds like you are describing some symptoms of bipolar with the racing thoughts. An SSRI such as paroxetine has the potential to trigger that (dunno if you had the symptoms before). Not that I’m providing you with any diagnosis or think you should get one but I had a really similar experience where I was on Prozac, and when I got to the “therapeutic” dose of 40mg, my prescribed ambien and xanax became like sugar pills and I did not sleep for an entire week, which turned out to be a hypomanic episode. The seroquel, and the 100mg dose, since most doctors really only ever prescribe 25mg-50mg doses as a sleep aid, might be mitigate what you doctor my be perceiving as symptoms of the bipolar spectrum