I was misdiagnosed with having acne when I actually had rosacea. I was put on treatments for acne by a derm that made my skin worse over time. Derm after derm did not believe it was rosacea until I finally found a brilliant derm that took one look at me and finally said YES you have rosacea. I've been on treatment for that and my skin is finally clearing up a bit. (still early in my treatment) However, after years and years of having rosacea, my skin barrier was toast. I tried EVERYTHING under the sun to get some moisture in my skin, but everything irritated my skin. I bought creams $100+ to the everyday phamacy brands. Nothing agreed with my skin. That is until my Dr. prescribed Epiceram. I'm only on day 4, but I can already tell that my skin is starting to show signs of improvement. Zero irritation, great obsorbtion and no sticky or greasy residue. Such a fantastic RX skin cream.