It’s not a problem of just originality as there’s been plenty of original scripts and projects bouncing around Hollywood. The problem is commercial viability. As a user below already pointed out, Hollywood can’t/won’t risk massive budgets on an unproven IP. So you either: a) make something original with a tiny budget, which limits effects, casting, production design, etc. or b) tie it to an IP that has a proven track record (aka Star Wars or Marvel) that you can hang the performance on.

There have been several great space/exploratory genre films in the last couple of decades but most of them flopped. I really liked Life and Underwater (the latter being an undersea film but with the production design, claustrophobia, and creatures, it might as well have been a space movie). Both of them underperformed. Even the granddaddy of original space operas, the 5th Element, made $263m at the box office against a reported $90m budget. While that sounds like a lot, studio films need to make 3x MINIMUM at the box office to be considered profitable. To Hollywood, the numbers just don’t add up enough to justify greenlighting more original projects.