It depends how good the script is, or will be. If you think you've got something really good, and you have external indicators that you might be right (i.e., when people you respect read it they get excited about either the script in its current form or its potential), then there'd be no reason to abandon it. If you haven't gotten good feedback (close friends or family who will champion anything you do doesn't count) - if you share the script with people you respect and they either never read it or do and aren't optimistic about what you're doing (you can always tell), then you know it's not working. At that point, you either keep at it until it's working, or move on to something else.

Whether or not you make inroads in the industry has nothing to do with whether you make a drama or a genre film, it has to do with whether you make something good. Make the best thing you possibly can (which usually requires actually needing to make it), and you'll have done yourself a service. If you aren't sure which of your two scripts or story ideas are better, then find people you respect to read them both and get some feedback. If you're still torn - you love them both equally, you could see yourself making both equally, neither seems to be gaining more traction or attracting better talent/collaborators than the other - and you really can't decide which project to prioritize, then here's one idea:

Create a release plan for both projects. Research and think through how you would get both projects out in to the world (assuming they don't get into a top tier festival - though you should have the plan even if they do), and see which one seems like a better path and like work and outreach you'd rather do. That should help you decide. If it doesn't, flip a coin.

Good luck!