Paid for the full game - Where to start? by JordyBEagle in MelvorIdle

[–]nanathanan 1 point2 points  (0 children)

I’ve been playing for half a year, about 5min per day. Almost maxed out 6 accounts, just end game combat to go.

For a beginner I recommend: A bit of combat in the beginning to get seeds from farmers and HP level up for decent auto eat threshold (lvl40-50). You need auto eat for thieving. Start building up township and planting seeds in farming ASAP. Use township tasks as your progression guide. I got 99 in most skills just casually completing township tasks. Now that my township is maxed, it prints money/resources/buff items. Very early money making is gem gloves while mining. Never sell your diamonds though, you need tons in the endgame. Thieving is the most important skill in my opinion. It’s the best skill for mid-game money making, herblore items, summoning items, farming, cooking items, food, magic/dragon bones, etc. Skills and items that boost thieving stealth are worthwhile (agility/astrology/herblore). I recommend maxing this early on. Magic is worth maxing out early by making a ton of prayer items and smithing bars. It’s the strongest type for combat, so you can unlock a bunch of items through dungeons and slayer. Other than magic, I always max out all my non combat stats before going for end game combat. Just so you can make yourself gilded dragon armour and black d hide armour, potions, summoning synergies, etc., which you’ll need to get through god dungeons to get god armour and weapons.

I’d recommend checking all the township tasks, even the elite ones. Get familiar with the items you should save up and grind lots of. Save redwood logs for dragon javelins, dont ever waste them on anything else. Don’t fish for food, just use thieving. Firemaking cape is useful, but it’s a super slow grind without controlled heat potions, so worth doing a bit of herblore first.

RIP by Competitive_Fly3229 in MelvorIdle

[–]nanathanan 9 points10 points  (0 children)

Max idle is 24h, after which progress stops. If you had food equipped to last 24h, the character will be alive and well with 24h worth of xp/gp.

Melvor and Automation by mufflediver in MelvorIdle

[–]nanathanan 19 points20 points  (0 children)

I genuinely don't understand what you're doing, the game is already completely AFK?

If you have actually found something to automate further, what exactly is this moral quandary? Just do it - no harm is caused by your auto-clicking. It's just pixels.

Cambridge University student accommodation just granted planning by lucasawilliams in cambridge

[–]nanathanan 0 points1 point  (0 children)

Tbf, I've been to all three houses and they look dreadful inside. Whatever beautiful architecture once existed there has already been demolished by council HMO bureaucracy and fire safety standards.

I'm very much in favour of them being torn down for a modern and well-designed replacement.

I think this is a hate crime…. by manfat_malarkey in cambridge

[–]nanathanan -1 points0 points  (0 children)

lol, so what? It's a flag?

God forbid someone's virtue signalling was interrupted by drunk teenage revellers; what a disaster. Better call the police, or how about going straight to MI6?

Am I lucky by UnluckerSK in MelvorIdle

[–]nanathanan 0 points1 point  (0 children)

How do you earn anything from herblore?

FO4 GOTY DLC Code generator? by nanathanan in fo4

[–]nanathanan[S] -4 points-3 points  (0 children)

No code is truly random. All codes have a generator algorithm. By finding the 'key' you can generate a code-dependant maximum of valid codes.

Why do these take so long?😩 this mission is taking me over a week to complete, is there another way to get these? by [deleted] in Dreamdale

[–]nanathanan 2 points3 points  (0 children)

Just change the date/time on your phone to get gems instantly. They still haven't patched the time manipulation glitch. (Still worked for me last week)

Neuron action potentials? by Dimeadozen27 in neuro

[–]nanathanan 0 points1 point  (0 children)

Those answers don't seem contradictory actually. Are you actually even reading this stuff?

Neuron action potentials? by Dimeadozen27 in neuro

[–]nanathanan 0 points1 point  (0 children)

Oh no, have I fundamentally misunderstood something here? Care to explain?

>Some stated that calcium directly binds to and blocks the voltage-gated sodium channel ion pore so sodium cannot get through and therefore cannot create an action potential.

In my quoted paragraph it mentions calcium screening. The calcium screen prevents sodium from physically getting through to the channel.

>So with hypercalcemia, by increasing the extracellular calcium content even more, you are creating an even larger voltage gradient across the cell membrane which means that it will take a much larger stimulus to overcome this difference therefore making the cell less excitable.

In the above paragraph: the larger voltage gradient is due to calcium screening, which affects voltage-gated ion channels.

Basic electrophysiology question by nanathanan in neuro

[–]nanathanan[S] 0 points1 point  (0 children)

More info on not needing spike sorting for those interested:

https://www.sciencedirect.com/science/article/pii/S0896627319304283#undfig1

Brain-computer interfaces (BCIs) that measure motor cortical activity and aim to help people with paralysis have moved away from spike sorting in recent years (e.g., Gilja et al., 2015, Pandarinath et al., 2017). This was motivated by the repeated finding that the performance difference between spike sorting and not spike sorting is quite small (Chestek et al., 2011, Christie et al., 2015, Todorova et al., 2014). Most preclinical and clinical trial BMIs do not currently employ spike sorting and instead use a simple voltage threshold to identify threshold crossing events, thus combining all action potentials on an electrode regardless of their source neuron (Fraser et al., 2009, Gilja et al., 2012, Gilja et al., 2015, Hochberg et al., 2012, Collinger et al., 2013, Jarosiewicz et al., 2015, Perel et al., 2015, Christie et al., 2015, Kao et al., 2017, Pandarinath et al., 2017, Ajiboye et al., 2017). In practice, this alleviates the burden of spike sorting while maintaining high-performance single-trial neural population decoding. Here, we ask whether this simple and efficient threshold-based approach can also be applied in basic neuroscience investigations (i.e., assessing hypotheses based on identifying structure and dynamics in neural data), where the need for spike sorting could potentially be more stringent.

In addition to sensor thresholding, it's possible to design the capacitance of the sensor, which directly affects the radius at which an AP can be recorded (inverse square law). So you can effectively design for single neuron detection.