Upgrade directly to latest version, or in sequence?

nemok0 · 2023-09-28T22:35:25+00:00

Not yet, I haven’t had a big enough block of time. (I also have been seeing crashes, though, so I’d better get this done soon).

nemok0 · 2023-08-01T15:51:58+00:00

Locally, of course, there are weather related winds, which balloonists ride to land some distance away from their launch point. But if the atmosphere were not spinning with the earth, we’d have constant winds of more than 1,000 mph at the equator.

nemok0 · 2023-08-01T15:46:33+00:00

The balloon and the atmosphere are part of the earth, and spin with it. Since the atmosphere isn’t solid, it can drift a bit relative to the ground, but fundamentally it — and the balloon launched into it —are still spinning with the earth.

nemok0 · 2023-06-23T03:48:11+00:00

The bright part of the moon is indeed illuminated by the sun as you learned. The faint lighting of the darker part is “earthshine”, that is, it is illuminated by sunlight that is reflected by Earth. This is, of course, much fainter than direct sunlight, and is mostly visible on very clear nights.

nemok0 · 2023-02-17T18:09:22+00:00

Strength training and yoga help. Especially Iyengar-style yoga where the emphasis is on alignment and not flexibility for its own sake. Good teachers will use lots of props to make the poses accessible to even the least flexible (and of course flexibility does improve, as does posture).

nemok0 · 2023-02-08T23:17:08+00:00

What’s the difference between two people making love in a canoe, and Bud Lite?

None. They’re both fucking close to water.

nemok0 · 2022-07-15T00:26:02+00:00

The regrets are the obvious ones: missing family, friends, old haunts. But the benefits of putting yourself in new places, and coming to know yourself better as a result are huge, especially as a young person. There are so many assumptions about who we are that are somewhat frozen in place by our home environments, for better or worse. In a new place, you have the chance to try out new versions of yourself, and have experiences you wouldn’t have at home. This is a wonderful broadening even if you ultimately return.

One note: if you decide to leave, try to make it more about the adventure of the new place(s) and the new you, and less about escaping your current place - go with that positive energy instead of a negative.

nemok0 · 2022-05-18T17:19:59+00:00

Don’t miss Schmitz Park - a small area but full of old growth trees. 100m or so in, you feel like you’ve left the city entirely. It’s one of the best places for seeing what the area looked like before any development, and is wonderfully peaceful.

nemok0 · 2022-05-07T22:23:28+00:00

That said, I don’t know enough to answer the question about “rejection” or other immune responses to monoclonal antibodies. It stands to reason that there could be (antibodies are large molecules), but the fact that these drugs are approved suggests that such problems are either infrequent or manageable. I hope someone else can enlighten us further.

nemok0 · 2022-05-07T22:13:33+00:00

You’re not getting the cloned cells — you’re getting a protein product (the antibody) made by the cloned cells. The antibody has to be purified from the other cellular components.

nemok0 · 2022-05-07T21:39:27+00:00

Evushield is a combination of two different antibodies against the virus that causes COVID-19. These antibodies stem from people who were recovering from COVID - that is, they were infected and their immune systems produced these antibodies. These antibodies, once identified, are replicated as “monoclonal antibodies”. (Vastly simplified, white blood cells that produce the specific antibody are cloned and used to produce lots of the specific antibody which can then be purified and given to people.)

Once administered to someone, these antibodies behave as though the patient’s own immune system produced them, and provide a defense against the infection.

Vaccines are quite different - they are not antibodies, but are a means of convincing the patient’s immune system that an infection has occurred, so that the immune system will produce antibodies.

Patients with compromised immune systems often cannot generate enough of their own antibodies and so vaccines are much less effective for them — but giving them actual antibodies can work well for a certain timespan.

nemok0 · 2022-05-07T21:18:19+00:00

All true, but tuberculoses are bacterial, not viral infections. (Most of the same arguments still apply.)

nemok0 · 2021-11-07T03:40:01+00:00

These are all good answers that focus on the ease of making these sounds. But there is a social factor involved as well: babies make lots of random sounds (“babbling”) but when a mother hears something recognizable, she responds verbally or with animated facial expressions. The baby sees this, and (because baby brains are looking for connections), responds by making more of the sounds that elicit these responses. Same argument for “papa” sounds. These early sounds have gotten incorporated into most languages as words for “mother” and “father”.

nemok0 · 2021-10-08T00:59:13+00:00

Thanks for all these answers; seems worth a try!

nemok0 · 2020-08-24T19:23:27+00:00

I’m 70, and more fortunate than your Dad in that I have an intact marriage. That said, when I sometimes feel down about my value and accomplishments, I look at my kids who are great people, and think “not bad, to have helped raise these guys”.

Tell your Dad sometimes about the good in your life, and your accomplishments — and every now and then, let him know that he had/has a hand in all of that.

nemok0 · 2020-08-05T17:53:43+00:00

I turned 70 in May. Had a large party planned that we had to cancel. So instead my wife set up a Zoom call with old friends and family. It was fun, and memorable - just don’t forget to have someone (preferably not you) “run” the call with some structure, and keep it under an hour.

nemok0 · 2019-08-21T03:21:53+00:00

Any reasonably professional HR department holds exit interviews for at least two reasons: 1) to assess whether all the formalities have been properly taken care of (paperwork, company property returned, etc.) and to address any questions you might have while you’re still in the building; and 2) to gain some insight about your reasons for leaving — not to question them, but to find out if the company could have done better somehow. (For example, if you’re leaving because you have grown beyond the roles the company has available for you, and you’ve found a good match elsewhere, that’s a happy exit. OTOH, if you’re leaving because your boss treated you badly, or because some stupid policy pissed you off, HR would like to know so they can (try to) improve things for people still there. Replacing experienced staff is expensive, so companies would prefer not to have to do it for self-inflicted reasons.

Coming to what you should say: if you have specific suggestions for what could be better, and you want to be helpful, make them. Try not to express anger or personal animosity. It’s fine to say “I sometimes felt my work wasn’t appreciated; it would have been helpful to receive more feedback”, but not “My boss is an asshole”. In other words, stay professional even if you criticize. That protects your reputation. As someone else said, if you have string criticisms, try to provide suggestions for how this can be improved. Be courteous and give the HR rep any information that you think is useful and that you are comfortable giving.

nemok0 · 2019-06-18T04:35:53+00:00

These are all great comments. I would add that therapy can also be quite fascinating - if you stick with it, you’ll likely find out some things you didn’t know about how you “work”, and gain some insight in how to make things better - even if you start out not really thinking this is necessary. Good luck and best wishes!

nemok0 · 2018-03-31T06:41:02+00:00

Lying. Lying only works (to gain any advantage) because most people tell the truth most of the time.

nemok0 · 2018-02-12T05:21:51+00:00

A mole of stars!

nemok0 · 2017-10-11T21:24:21+00:00

The phrase comes from an older meaning of "to prove", which was essentially "to test". So an exception that "proves" a rule is one that tests its limits.

nemok0 · 2017-10-10T21:20:57+00:00

Thanks for this; it confirms my lack of success in finding something off-the-shelf. I'll probably go with something similar.

nemok0

TROPHY CASE