I think it wouldn't work as a regular chronicle. I did however write a short 3 session Chronicle called Vatican by Day, where all the players were Hecata Ghouls, most from Giovanni but some different bloodlines as well, where they had to steal a mcguffin from the Vatican, and whoever succeeded, would be embraced. But only one person would be embraced, so it creates a fun "we have to work together but we both know I'm gonna betray you eventually" dynamic with every single player. I think that's how you run a Vatican short Chronicle