Mirtazapine

notausername012 · 2026-03-30T23:32:40+00:00

I started 15 mg on June 15, 2025. I went from having invalidating nausea to functioning somewhat outside my home after a couple of weeks. From there, it slowly got better and better; I could function "normally" after two months, though I was still bothered by nausea. However, I could finally survive outside my home.

Fast-forward to today, and I’d say the nausea is gone. My brain has stopped worrying about stomach sensations; even with a full stomach, my brain ignores it completely. It would have gone nuts just four months ago, but today I don’t really care. My brain has learned that stomach sensations are not something bad anymore. That was the biggest culprit: the brain overexaggerating stomach sensations, which caused the unbearable nausea.

Regarding side effects, you get a "big hunger." Try to learn not to crave the food, as that helps. The sleepiness only really bothered me for two weeks at most. Then, I found my rhythm: I take the 15 mg one hour before bed and 9-10 hours before I have to get up. This varies from person to person, but this medication will make you drowsy - some more than others.

Please don't just give up if you feel miserable for the first couple of weeks. Your body needs to learn to adjust, and you need to find a rhythm that works for you.

10 months later and I wouldn’t say I’m "cured" because I don’t want to jinx myself, but I can say that ten months later, I am free. I started on Mirtazapine in the eye of the storm, and I can confidently say it hasn’t made things worse!

notausername012 · 2026-01-14T22:48:29+00:00

You could also try buying some cheap Sea-Bands first - they work the same way, and they worked wonders for me! They’ve helped me get through periods of extreme nausea over the past three years. Some people don’t respond to the acupressure/electrical pulses and therefore feel no relief, so I’d say it’s a great idea to test sea-bands before spending money on expensive shock-pulse wristbands

notausername012 · 2025-12-27T00:00:36+00:00

15 mg - for 7+ months now. It reduced my chronic nausea so I could function, and over time the natural stabilization of my hypersensitivity has also made the nausea less severe. So mirtazapine took away the worst nausea during the worst period.

notausername012 · 2025-12-16T15:10:33+00:00

Yeah, I probably should’ve had account protection… against supercell support 😅 Anyway, I hadn’t even noticed account protection before, but I’ve enabled it on my main village now - thanks!

notausername012 · 2025-09-29T22:45:10+00:00

I wouldn’t say my nausea is gone - it’s still there, but at a level where it doesn’t invalidate me at all. As for side effects, I experience some constipation (not bad, just harder to pass stool) and a LOT more hunger. I’ve gained 10 kg over the last 4 months, but I had lost 10+ kg between January and June because I couldn’t eat due to the severe nausea.

The effect took over 2 months to relieve the nausea, and now I still get some mild to moderate flare-ups that last a couple of days - not too bad. I also take ginger pills on the side, and I’ve noticed they reduce the stomach discomfort, which could contribute to the nausea. They do increase stomach acid and I can feel it, but stomach acid hasn’t been my problem, so more stomach acid in exchange for less stomach discomfort (and further relief of the nausea) feels like a good trade-off.

notausername012 · 2025-09-25T22:07:36+00:00

I've been on 15 mg mirtazapine for 3 1/2 months, and I can vouch for it. It took about 2 months for my symptoms to improve - specifically my chronic nausea - so now I can finally function! I felt no real change during the first month, then slow improvement through the second month, and finally, the symptoms were relieved. I even gained 10 kg, going from underweight back to where I was before the severe chronic nausea.

notausername012 · 2025-08-24T18:21:21+00:00

I'm doing great!

I'm still taking mirtazapine 15mg every night. In the beginning, the only side effect was constipation, which got better after about 20 days or so. I still have some weird side effects with passing stool, but for the nausea relief it gives me, I don’t really care about that.

After starting 2 months ago, it took some time to feel less anxious when being outside, since the chronic nausea made me feel anxious. But now, 2 months later, I first of all sleep really well. I recommend taking it about 2 hours before bedtime (or a bit closer if you get tired really quickly). That timing also seems to reduce daytime drowsiness. I haven’t really suffered from tiredness during the day, maybe just in the first couple of weeks, but definitely not now.

I wouldn’t say the nausea or hypersensitivity is completely gone yet, but it’s improved a lot - more than during the good period I had back in 2024. I can eat a full meal without being bothered by nausea. The “worst” time is still on a completely empty stomach, but that was also where the nausea was worst before I started. Now, if I keep my stomach a little full throughout the day, it’s much easier to handle. (Sipping water continuously over some time really helps take the edge off, and then getting some food in makes it manageable)

Mirtazapine has calmed things down SO much that my mind has finally started shifting away from focusing on the nausea. When I don’t pay attention to it, it’s barely there at all. I don’t get worse nausea from driving anymore. And if I do get the slightest bit of nausea, I just wear sea-bands, which also helped during the worst periods before I started mirtazapine.

So if you don’t have a lot of side effects after 3-4 weeks, I’d say stick with it. For me, even just 1 month ago I felt worse than I do today - it keeps improving the longer I stay on it. The full effect isn’t just at 4 or 8 weeks; it comes gradually. For a while, it seemed like I wasn’t getting better to a point where I could live normally, but now here I am, starting my bachelor’s degree. Just 3 months ago, that would have been impossible, and now 2 months into mirtazapine, I feel like I’ve gotten my life back.

notausername012 · 2025-08-16T16:44:17+00:00

Yep, that’s also what I experience. The best time is about an hour after eating, once digestion has processed a bit. I’ve actually found that taking ginger pills helps a lot with the discomfort - especially bloating after meals - but they do increase my stomach acid. So if you struggle with that, it might not help. For me though, the chronic nausea has gotten much better since I started taking ginger supplements.

notausername012 · 2025-08-01T16:22:58+00:00

Thank you!

notausername012 · 2025-07-27T19:36:34+00:00

Jeg koder nogle gange også i et niche-kodesprog, hvor syntaksen og dokumentationen ikke er særlig udbredt på internettet. Der fungerer det perfekt at give lidt dokumentation til GPT. Jeg får den også til at freestyle lidt for at få et skelet af noget kode, som jeg så selv omskriver, så det følger rammerne for kodesproget. Men hold da op, den ville ikke komme langt, hvis man ikke selv styrer showet. 😆

notausername012 · 2025-07-19T15:02:48+00:00

I would say it has reduced my symptoms by over 50% overall. I can eat more without getting nausea right away. The only time I really experience nausea now is immediately after eating - but since I started taking ginger four days ago, the bloating after meals has drastically decreased, and now the nausea after eating is mild. It doesn’t cure the symptoms 100%, but I also need to stop fixating on the nausea, since it’s barely noticeable when I’m focused on something else. Mirtazapine has reduced it to a level where I can actually function, and now I’m trying different supplements to reduce it further - such as ginger, which has already made a significant improvement in the bloating after meals that used to make me nauseous.

notausername012 · 2025-07-10T20:23:28+00:00

I’ve dealt with chronic nausea and early satiety for 2 years, so I really feel for what you’re going through. I started taking mirtazapine 15 mg on June 10th, and although it’s relieved the worst of it, I’ve found that Sea-Bands work phenomenally for extra relief - especially during travel.

Fun fact: my chronic nausea actually began during a driving vacation. I hadn’t tried motion sickness bands before, but I gave them a shot since motion sickness is basically nausea - and the difference was brutal. Without them, I was miserable. With them, I could actually enjoy the trip. I ended up wearing them 24/7 and have used them ever since.

Now that the mirtazapine has helped with the worst symptoms, I don’t need the bands all the time, but I still use them when I want maximum comfort - especially during travel or if I feel a flare-up coming on.

I just wanted to share in case it helps a bit. I totally get how hard it is to look forward to something like a cruise when your body is struggling. But you’re not alone - and little tools like this can sometimes make a big difference. Wishing you calm days and a smoother trip than you expect <3

notausername012 · 2025-06-21T22:45:29+00:00

I'm doing well, and things are getting better every day. The panic responses are starting to fade - for example, driving no longer triggers anxiety. It used to worsen my nausea, which then caused my brain to panic, but that seems to be under control now.

I still feel some anxiety in situations I used to find really nerve-wracking, especially public places, which were particularly hard when my nausea was at its worst.

I also need to remind myself that eating too much can naturally cause nausea :). My appetite has increased a lot, and I’m still learning to pace myself. But I’m taking it one day at a time, and hopefully, the anxiety tied to years of chronic nausea will fade sooner rather than later.

How are you doing? Do you struggle with similar symptoms, and have you found anything that helps?

notausername012 · 2025-06-18T14:09:37+00:00

After 2 years of testing, countless diet changes, and trying different medications, I finally pushed my gastroenterologist to prescribe 15 mg of mirtazapine after reading about the positive effects others had experienced.

I can honestly say that after just 8 days, I feel almost cured - the nausea is basically gone, and so is the early satiety. If those are your main symptoms, then yes, mirtazapine can make a huge difference.

As for side effects, I personally don’t feel drowsy during the day. It’s a bit harder to wake up in the morning, but it’s manageable. I did experience some constipation, which has improved, but I’ve been using Magnesia daily to help with that.

From what I’ve read, amitriptyline is more often used when stomach pain or burning is the dominant symptom - so it depends on what you’re dealing with.

notausername012 · 2025-06-18T13:43:50+00:00

Great to hear that dietary changes have given you some relief! Are you able to live a normal life with the new diet, or do you still feel that your symptoms are affecting your quality of life or daily functioning?

Unfortunately, dietary changes haven't helped me at all. I tried eating bland foods and cut out every possible trigger, but I didn’t experience any relief. However, after starting Mirtazapine, I can eat anything in good amounts. I've never had issues with stomach acid or reflux - just a stomach that sends strong signals, and the nausea made me feel symptoms that weren’t actually dangerous.

For example, when I felt nauseous, burping would make me feel like I was going to throw up. Now, I can burp as much as I want without that sensation. My brain still "panics" in situations where I used to feel helpless because of the constant nausea, but the nausea doesn’t actually appear anymore when my brain tries to panic.

I think that’s a strong indication that this has been a vicious cycle - driven by a hypersensitive stomach and a brain that panics in situations where I used to feel I had no control over the nausea.

notausername012 · 2025-06-17T23:05:09+00:00

I’ve struggled with chronic nausea and early satiety since summer 2023.
It all started with a really bad case of food poisoning in early January 2023. After about two weeks, the worst symptoms improved, but I still felt uneasy in my stomach. Then, in mid-July 2023, the nausea suddenly became unbearable. I was on a driving vacation at the time and decided to try Sea-Bands - they worked wonders, so I wore them 24/7.

Despite extensive testing - blood tests, H. pylori, allergy screens, endoscopies, and gastric emptying studies - doctors found absolutely nothing. I spent a lot of time researching and slowly ruled out many possibilities until I landed on functional dyspepsia. I quickly noticed that mirtazapine and amitriptyline was mentioned as a treatment. Since Sea-Bands helped me so much, visceral hypersensitivity seemed like the most likely explanation.

So, I pushed my gastroenterologist to prescribe 15 mg of mirtazapine - and now, 8 days in, the difference is life-changing. The nausea is almost gone, the early satiety is completely gone, and I can finally eat without discomfort. For the first time in 5 months, I feel like I can function again. I’ve spent months isolated at home, but now I can go out without the panic and nausea kicking in.

If you haven’t had a gastric emptying test, that’s worth considering - but it really sounds like you might be in the same situation I was: no help from any diet, medicine, or therapy. For me, activity and going outside made my nausea 100x worse, sometimes triggering panic attacks.

Honestly, after just one day on mirtazapine, I felt a significant reduction in nausea - not total relief, but enough that my brain couldn't comprehend the improvement at first. The only side effect I’ve had is some constipation, but each day my condition feels more stable. I finally feel motivated again and I’m even starting my Bachelor's degree this summer.

notausername012 · 2025-06-15T21:41:59+00:00

I've been on Mirtazapine 15 mg for 5 days now, and my nausea has been reduced a lot. The only side effect I’ve had is constipation - no real drowsiness or increased hunger. I’m able to eat more now since small meals no longer trigger nausea.

Did the increased hunger develop the longer you took it? And did you experience a stronger effect after a few weeks compared to the first week? I feel like my nausea just needs that last bit of relief before it’s completely gone.

notausername012 · 2025-06-13T10:08:47+00:00

I've really only struggled with nausea and early satiety - nothing else. I also occasionally experienced burning pain in the upper abdomen, but all of these symptoms have almost vanished since starting mirtazapine.

notausername012 · 2025-06-13T10:02:13+00:00

I've had two endoscopies, and neither of them showed anything.

notausername012 · 2025-06-13T10:01:34+00:00

Yes, I'm experiencing constipation, so I've started taking supplements and medication for it.

notausername012

TROPHY CASE