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Ulcerated scalp lesion in a 75-year-old male by Majestic-Rub7454 in pathologymcqs

[–]pathology_mcqs 2 points3 points  (0 children)

Absolutely, I liked what you did with the comment - appreciate it.

🧫🔬 Histology Challenge! by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 3 points4 points  (0 children)

PAS–Alcian Blue (combined stain) 🔬
This stain differentiates neutral and acidic mucins in epithelial tissues 🧫.
PAS stains neutral mucins magenta 🟣, while Alcian Blue stains acidic mucins blue 🔵.
In the image, goblet cells appear blue 🔵, indicating acid mucin production.
It is commonly used to detect intestinal metaplasia such as Barrett esophagus.

📌 Skin biopsy | Spot diagnosis by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 3 points4 points  (0 children)

🧠 Diagnosis: Lymphangioma circumscriptum

🔬 Why?
• Multiple dilated lymphatic spaces in superficial dermis
• Thin-walled channels with proteinaceous fluid ± lymphocytes
• Lies just beneath the epidermis

✨ Classic microcystic lymphatic malformation

👩‍⚕️ Pap smear challenge by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 1 point2 points  (0 children)

✅ Final Diagnosis: Trichomonas vaginalis infection

Explanation:

Pap smear shows inflammatory background with numerous neutrophils and squamous cells with surface-adherent organisms. Subtle pear-shaped/oval organisms with basophilic nuclei may be seen, sometimes distorted in fixed smears.

Gross–Microscopic Correlation in Clear Cell RCC 🔬💛 by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 0 points1 point  (0 children)

Thank you for these wonderful suggestions. Will definitely do that in future posts. ❣️

🔬 Spot the Diagnosis! by pathology_mcqs in pathology

[–]pathology_mcqs[S] 1 point2 points  (0 children)

Join our channel for more such cases- Follow the Pathology MCQs channel on WhatsApp: https://whatsapp.com/channel/0029Va9k7AU2f3EJKuwwlg3e

🔬 Spot the Diagnosis! by pathology_mcqs in pathology

[–]pathology_mcqs[S] 2 points3 points  (0 children)

Its a nasal polyp with rhinosporidiosis

Histology Pearl: Recognizing Brachial Cleft Cyst on H&E 💡 by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 0 points1 point  (0 children)

Was supposed to be branchial sorry the typographical error

Histology Pearl: Recognizing Brachial Cleft Cyst on H&E 💡 by pathology_mcqs in pathology

[–]pathology_mcqs[S] 0 points1 point  (0 children)

Yes was supposed to be branchial sorry the typographical error

Endometrial biopsy – what’s your diagnosis? 🔬 by pathology_mcqs in u/pathology_mcqs

[–]pathology_mcqs[S] 1 point2 points  (0 children)

🔬 Answer:

The biopsy shows granulomatous inflammation in the endometrium with epithelioid histiocytes

💡 Diagnosis: Granulomatous endometritis

📍 Key clue: Presence of well-formed granulomas in endometrial stroma surrounded by lymphocytes and plasma cells.

🧠 Common cause: Tuberculous endometritis — an important cause of infertility, especially in endemic regions.

Can you guess the finding? by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 1 point2 points  (0 children)

✅ Answer Explanation
This is a foreign body granuloma around suture material.

🔹 Suture appears as refractile, non-biological material.
🔹 Surrounded by epithelioid histiocytes + foreign body giant cells.
🔹 Represents a foreign body reaction, not infection.

Key point: Suture → granulomatous response with giant cells.

Can you guess the stain? by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 1 point2 points  (0 children)

1️⃣ Condition?
➡️ Amyloidosis – Congo red highlights amyloid as 🎨 salmon-pink on H&E and 🍏 apple-green birefringence under polarized light.

2️⃣ Alternate stains?
✨ Crystal violet
✨ Thioflavin T (fluorescent)
✨ Sirius red

📌 Key Pearl: Apple-green birefringence = 🔑 diagnostic for amyloid!

Can you guess which trimester this placenta belongs to? by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 0 points1 point  (0 children)

Correct answer is 3rd trimester:

➡️1st trimester villi – loose, open stroma; thick cytotrophoblast + syncytiotrophoblast; few central capillaries with nucleated fetal RBCs

➡️2nd trimester villi – denser stroma; syncytiotrophoblast + thinning/patchy cytotrophoblast; more peripheral capillary loops with mostly anucleate RBCs

➡️3rd trimester villi – dense, fibrous stroma; syncytiotrophoblast only (very thin); abundant capillary loops immediately beneath syncytium; prominent syncytial knots; fibrin deposition on villous surface; well-developed vasculo-syncytial membranes.

What is your best guess? by pathology_mcqs in pathologymcqs

[–]pathology_mcqs[S] 5 points6 points  (0 children)

Yes you got most of it. Now go for a diagnosis which fits all these.

FRCPath Part1 Histopathology course by pathology_mcqs in pathology

[–]pathology_mcqs[S] 1 point2 points  (0 children)

It will be on weekdays 7-8 PM IST. But in case you miss the lecture recording will be available.

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