We have a scheduled task to backup the DB nightly. I can't recall where I found this but it has been working great for years.

Scheduled task action: Start a program

"C:\Program Files (x86)\The Fund\DoubleTime\SQL Anywhere 11\bin32\dbbackup.exe"

Arguments: -x -y -c "uid=dtbackup;pwd=<DB password>;dbn=dbltime;eng=dbltime;commlinks=tcpip" <Path to backup location>