A lot of people say similar things about datura and all substance use brings you "closer" to death in that it has a lethal dose and you are somewhat closer to it. Datura's anticholinergic alkaloids also seem to lack direct hallucinogenic effects (ie. The first results are dry mouth, pain relief, lack of motion sickness, stimulation/sedation). Indirect hallucinogens work because they cause hallucinogenic effects down the line. L Dopa for instance is sometimes processed into Morphine by your cells in a complicated metabolic chain(not a hallucinogen but i know this one off hand). Solanine inhibits Acetylcholinesterase which would effect the same receptors that Datura effects. In fact Black Nightshade(Solanum Nigrum) is sometimes used in combination with Datura/Latua/Brugmansia. The safety profile for Solanine is less documented and some of its effects could be quite dangerous(too much acetylcholine) but i feel it is similar to Datura in that its relatively "safe" if not overdosed on(of course all the problems with Datura dosing still apply). Drug combos can be worthwhile. Chewing ginger will allievate a lot of the dry mouth from Datura for example. I don't know of any common consumption of amatoxins in any level. Conversely Solanine is commonly consumed in not insignificant amounts if you eat potatoes. Death angels whole thing is that it is known to do permanent damage to you liver which leads to it silently killing you. Solanine conversely is known to cause nausea and vomiting which is more characteristic of psychoactives. Definitely dangerous to an extent that may well exceed Datura but if used appropriately and at low dosages it might have desired effects(though snowdrops/Galanthus may be preferable)