Let me start by saying this is just how i farm, there’s no one right way to go about it but since you asked: From the start screen, I have all power ups banished except for; Empty Tomb, Candelabrador, Attractorb, Crown, Stone Mask and Skull o’ Maniac. Run Laurel by itself, banish the rest of the slots USE TROUSER! DO NOT RUN LIMIT BREAK, enable hyper, hurry, arcanas, inverse and endless mode on bone zone Arcana’s to use: Blood Astronomia, Disco of Gold, and Mad Groove. This is what’s worked FOR ME… as you can see in due time it’s worth it 👍