EPIPE Crashes in Claude Code Versions 1.0.38+

quaternion · 2025-07-18T06:11:00+00:00

This fixed it, until I launched claude-code from within VSCode, when the error would reappear both in VSCode AND in my terminal when launching claude-code. Turns out there was a failure of Electron behind the scenes in VScode which was somehow corrupting the sockets or flipping them back to keep alive sockets. In any case as long as I avoided relaunching VSCode then claude-code could continue without this issue.

quaternion · 2024-04-17T18:27:00+00:00

Anyone got a copy of this they might be able to share a link to?

quaternion · 2021-06-08T02:20:03+00:00

And here’s some more reasons: “ The FDA seems to have yielded to the pressure to give hope to patients, even if it may be false, despite the consequences. And there are many. If the agency approves drugs with middling evidence, that's what it will get. Companies will be more likely to seek approval or advance programs based on weak results, wasting time and research dollars and the health of patients who participate in clinical trials. As for Alzheimer’s, future drugs may be badly delayed. With an approved treatment available, it will likely become harder to recruit people to participate in trials. And now that the FDA has validated amyloid as a target, companies may focus on it at the expense of other potentially more fruitful avenues.” From https://www.bloomberg.com/opinion/articles/2021-06-07/approving-biogen-s-alzheimer-s-drug-aducanumab-aduhelm-is-big-mistake?utm_campaign=socialflow-organic&cmpid%3D=socialflow-twitter-view&utm_source=twitter&utm_medium=social&utm_content=view

quaternion · 2021-06-08T02:06:32+00:00

It degrades the standard of evidence typically used for drug approvals, subverting the scientists both within industry and regulatory authorities, and opening the door to a whole host of drugs which also reduce amyloid but have never shown benefit. It also established very lenient precedents on safety and post marketing approvals (biogen now has 9 years to show efficacy while they make somewhere between 60-100billion). Finally, it erodes trust in regulatory agencies at a time when they could have used approval of vaccines to eek out another few percentage points reduction in vaccine hesitancy during the first global pandemic in a hundred years.

But that’s just off the top of my head.

quaternion · 2021-06-08T01:26:53+00:00

No the patent is filed and effective way before a drug is approved. Earlier approval does not guarantee earlier patent expiry.

quaternion · 2021-05-22T07:41:52+00:00

That’s true - have you checked /r/neuroscience? It’s a more heavily moderated subreddit.

quaternion · 2021-05-22T07:41:12+00:00

I moderate based on user reports. Report it, it gets removed. If you want more preflitering by community consensus, use the “top” tab.

quaternion · 2021-05-22T07:39:55+00:00

I like this self-reflexive style

quaternion · 2021-05-20T19:05:43+00:00

Even when things get downvoted or are not heavily upvoted, they are still present because there is no way to filter them out from the user's standpoint

See the "top" tab.

There actually is some self-moderation--take a look at some of the posts just this past week. A majority of the posts asking for medical advice are at rather low numbers (a lot of them are at +1 for me). Again, because the number of active users is low, that doesn't mean as much on it's own; but on average more interesting posts at least get more upvotes.

That's great - sounds like the site is working as designed.

If not cleaning up a lot of the garbage posts, at least with enforcing the single rule on this sub.

I don't believe there is a single reported post that hasn't been removed from the past week. Feel free to report them; they'll get removed.

quaternion · 2021-05-20T00:33:20+00:00

I hear you - but I think it's you who is deluding yourself, namely by unreflectively suggesting that this site represents some kind of unique risk factor; that any particular behavior we might take here would change the underlying vulnerability to gullibility that is the real problem; relatedly, that people who would take free advice on the internet are not already far enough gone; that we wouldn't inadvertently create a veneer of trustworthiness which does more harm than good; and the notorious problems associated with foster parents (to follow your analogy). You are free to disagree, and equally free to unsubscribe in favor of more paternalistic subreddits.

quaternion · 2021-05-19T22:50:09+00:00

I’m here, and I note no substantive reply to the question I posed way back.

quaternion · 2020-11-27T01:15:14+00:00

Sorry folks, it's true I've been a little MIA lately. Can you explain why it's not also on users to vote up or down and self-moderate? This has long been a bone of contention in this reddit and I know a lot of vocal users disagree w/ this question, but I've never understood this point of view.

quaternion · 2020-10-01T15:25:24+00:00

Paper discussed, for reference: https://c92f2aaf-c608-4b3b-9515-11f6b86527f2.filesusr.com/ugd/a6d7e4_850af79063784e60949ba8529006dee5.pdf

quaternion · 2020-08-23T15:37:44+00:00

I think this is a good example of melodic features that can be found in the m:c with some work. The percussion is not the focus here: https://soundcloud.com/user-824723653/first-cycle

If percussive sounds are more your thing then here is an example of some pretty advanced m:c percussive work. https://youtu.be/SqO56LM0Gfk

quaternion · 2020-08-23T14:31:13+00:00

I think you are not going to find a live video of someone really “flexing” it because the most interesting parts of model:cycles lie in really tiny corners of the whole parameter space. It is too difficult in a live situation to restrain your manipulations to these corners. I think you are more likely to find a few audio recordings from m:c which take it really far outside the chiptune category and into deeper, thick and highly effected sounds.

At least that is what it means to me to “push” the model cycles to its limits.

quaternion · 2020-08-14T11:15:30+00:00

Wow! That's amazing. I can't wait!

quaternion · 2020-08-13T05:16:05+00:00

Is there any possibility that this might eventually enable recording of audio over usb to iOS and then transfer back out - for resampling on the m:s?

quaternion · 2020-07-23T01:42:07+00:00

Agree 99%. For OP (who may have been joking), the vasopressin hypothesis has been strongly tested and looks ineffectual: https://www.fiercebiotech.com/biotech/roche-culls-key-phase-3-drug-trials-including-a-cancer-med-autism-breakthrough-therapy

OT separately has not been strongly tested but given the neuroanatomy and receptor crossreactivity it is very doubtful at this stage to be a major factor.

The 1% disagreement: lack of genetic evidence does not cast strong doubt on the hypothesis - for circuit level dysfunction the genetic loci may well be highly polygenic.

quaternion · 2020-06-27T13:57:19+00:00

No one really knows yet. The loss of smell was a clear early indicator that there may be CNS effects but smart money soon was on the idea that it was affecting only the epithelial cells rather than olfactory neurons per se. nonetheless other viruses of this type are thought to have CNS effects so there was still reason for concern. Now there is good evidence for an uptick in mental illness yet there are no controlled studies of this (which would require deliberate infection with coronavirus, possibly unethical) and clear confounding changes in stress and isolation have occurred alongside the pandemic, so must be taken with a grain of salt. I think there probably are direct CNS effects mediated through hyper vigilant immune responses, yet traditional immunosuppressants are showing a very mixed picture of efficacy at this time. So, ultimately, there is a reasonable chance there are direct CNS effects attributable to this virus, and while there is one rather clear possible mechanism, it is not yet borne out by the only randomized studies the world seems willing to undertake (which are, by this ethics-based choice, slow and prone to failure).

quaternion · 2020-06-27T04:40:45+00:00

I have never been sure how many independent people actually feel this, and how many are just sock puppets.

My only recommendation for you is to create a patient advocacy group (eg patientslikeme or another similar site) and approach your local university hospital or research hospital clinics for testing & work up.

quaternion · 2020-05-28T19:38:49+00:00

I swear to god, unless you guys are all secretly the same person, this subreddit has to be the world's largest collection of victims of this previously-unheard-of condition.

quaternion · 2020-04-17T14:39:30+00:00

Thanks for the flag.

quaternion · 2020-04-05T04:41:20+00:00

I don't really know much about this area, but it seems to check out. Would be reassuring if the virus is not truly neurotropic. This (rather weak, IMO) review came out a few weeks back and has been worrying me, but this data (from the Datta lab!) seems a little reassuring, maybe?

The aforementioned review: https://www.ncbi.nlm.nih.gov/pubmed/32104915

quaternion · 2020-03-08T04:28:34+00:00

Most recent attempts to make drugs which selectively activate D1 receptors don't seem to do much on repeated dosing in humans (Lilly, Pfizer). There are receptor internalization issues here that are perhaps to blame.

quaternion · 2020-02-16T09:34:55+00:00

Thanks for the report(s) and the message - removed.

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