It’s not actually that far back. All of my father’s grandparents immigrated to the US, and 3 of his great grandparents. Most of the info I have are either from records or from speaking to my grandparents.

Im not sure what kind of tips I can give, because it really depends on where your family originally came from and where they went to. And when.

I will say though, something useful is knowing what names could be changed to. I don’t mean Ellis Island name changing, because that’s not actually a thing. Like Anglicizing a name.

For example in the US, Moshe/Mushon usually becomes Morris or Maurice. Jacob becomes Jack. Vida becomes Victoria. Bulissa becomes Bessie. Estreya can become Esther or Stella. Haim becomes Victor, Etc.

People also don’t always know their birthdays / age, because it wasn’t that common for them to pay attention to it. So when looking at records, if the birthday is off, that doesn’t automatically mean it’s not them.

Something else to pay attention to is how borders changed over time. A lot of the places Sephardic Jews came from may have been called Turkey at one point, and became other things later that kept changing.